Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| F8VSL7 | STOM | Stomatin | Homo sapiens (Human) | 168 aa |
Protein Details: F8VSL7 (STOM)
Protein Information
| Accession | F8VSL7 |
|---|---|
| Protein Names | Stomatin |
| Gene Symbol | STOM |
| Organism | Homo sapiens (Human) |
| Length | 168 aa |
| Isoforms | No isoforms |
| Related PMIDs | 19137006 29575903 31251020 32944167 36430497 31251020 (mass) 32651440 (mass) 36430497 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MAEKRHTRDS11EAQRLPDSFK21DSPSKGLGPC31GWILVAFSFL41FTVITFPISI
51-10051WMCIKIIKEY61ERAIIFRLGR71ILQGGAKGPG81LFFILPCTDS91FIKVDMRTIS
101-150101FDIPPQEILT111KDSVTISVDG121VVYYRVQNAT131LAVANITNAD141SATRLLAQTT
151-168151LRNVLGTKNL161SQISSLRL
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 30 | SWISSPALM DBPTM CYSMODDB | - | - | - |
GPS-Palm: 0.66
Deep-Palm: 0.94
|
| 53 | - | - | - |
GPS-Palm: 0.91
Deep-Palm: 0.86
|
|
| 87 | SWISSPALM DBPTM CYSMODDB | SPFH domain / Band 7 family |
HeLa
(29575903)
| - |
GPS-Palm: 0.76
Deep-Palm: 0.97
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.400
4
cerebral cortex
Specificity: 0.364
4/4 (100.0%)
2
HeLa cell
Specificity: 0.182
2/2 (100.0%)
2
Jurkat T cell
Specificity: 0.182
2/2 (100.0%)
1
LNCaP
Specificity: 0.091
1/1 (100.0%)
1
PC3
Specificity: 0.091
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
1
LNCaP cells (Mass)
Specificity: 0.091
1/4 (25.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 30 | C → C | 0.001887 | SNP | Silent | UCEC |
| 70 | R → C | 0.004283 | SNP | Missense Mutation | SKCM |
| 215 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |