Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| F8VTZ0 | PCBP2 | Poly(rC) binding protein 2 | Homo sapiens (Human) | 64 aa |
Protein Details: F8VTZ0 (PCBP2)
Protein Information
| Accession | F8VTZ0 |
|---|---|
| Protein Names | Poly(rC) binding protein 2 |
| Gene Symbol | PCBP2 |
| Organism | Homo sapiens (Human) |
| Length | 64 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 32944167 |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MDTGVIEGGL11NVTLTIRLLM21HGKEVGSIIG31KKGESVKKMR41EESGARINIS
51-6451EGNCPERIIT61LAGP
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 54 | SWISSPALM DBPTM CYSMODDB | KH domain | - |
cerebral cortex
(36430497)
LNCaP
(31251020)
|
Deep-Palm: 0.55
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.750
3
PC3
Specificity: 0.750
3/3 (100.0%)
1
LNCaP
Specificity: 0.250
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 109 | C → W | 0.002545 | SNP | Missense Mutation | GBM |
| 148 | I → Cfs*9 | 0.002288 | DEL | Frame Shift Del | STAD |
| 305 | R → C | 0.002020 | SNP | Missense Mutation | PRAD |
| 314 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |