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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
F8VW21 RPLP0 Large ribosomal subunit protein uL10 … Homo sapiens (Human) 244 aa

Protein Details: F8VW21 (RPLP0)

Protein Information
Accession F8VW21
Protein Names Large ribosomal subunit protein uL10 (60S acidic ribosomal protein P0)
Gene Symbol RPLP0
Organism Homo sapiens (Human)
Length 244 aa
Isoforms No isoforms
Related PMIDs 29575903 31251020 32944167 36430497
Database Sources CysModDB dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.846
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
33
LNCaP cells
Specificity: 0.846
33/46 (71.7%)
4
PC3 cells
Specificity: 0.103
4/4 (100.0%)
2
Cerebral cortex
Specificity: 0.051
2/4 (50.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MPREDRATWK11SNYFLKIIQM21QQIRMSLRGK31AVVLMGKNTM41MRKAIRGHLE
51-10051NNPALEKLLP61HIRGNVGFVF71TKEDLTEIRD81MLLANKVPAA91ARAGAIAPCE
101-150101VTVPAQNTGL111GPEKTSFFQA121LGITTKISRG131TIEILSDVQL141IKTGDKVGAS
151-200151EATLLNMLNI161SPFSFGLVIQ171QVFDNGSIYN181PEVLDITEET191LHSRFLEGVR
201-244201NVASVCLQIG211YPTVASVPHS221IINGYKRVLA231LSVETDYTFP241LAEK
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
99 Experimental CYSMODDB SWISSPALM DBPTM Prediction (High) Insertion domain in 60S ribosomal protein L10P 29575903
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
27 C → R 0.001887 SNP Missense Mutation UCEC
44 R → C 0.001887 SNP Missense Mutation UCEC
48 R → C 0.002033 SNP Missense Mutation LUSC
273 S → C 0.003460 SNP Missense Mutation CESC