Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| F8VW21 | RPLP0 | Large ribosomal subunit protein uL10 … | Homo sapiens (Human) | 244 aa |
Protein Details: F8VW21 (RPLP0)
Protein Information
| Accession | F8VW21 |
|---|---|
| Protein Names | Large ribosomal subunit protein uL10 (60S acidic ribosomal protein P0) |
| Gene Symbol | RPLP0 |
| Organism | Homo sapiens (Human) |
| Length | 244 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 31251020 (mass) 32651440 (mass) 36430497 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MPREDRATWK11SNYFLKIIQM21QQIRMSLRGK31AVVLMGKNTM41MRKAIRGHLE
51-10051NNPALEKLLP61HIRGNVGFVF71TKEDLTEIRD81MLLANKVPAA91ARAGAIAPCE
101-150101VTVPAQNTGL111GPEKTSFFQA121LGITTKISRG131TIEILSDVQL141IKTGDKVGAS
151-200151EATLLNMLNI161SPFSFGLVIQ171QVFDNGSIYN181PEVLDITEET191LHSRFLEGVR
201-244201NVASVCLQIG211YPTVASVPHS221IINGYKRVLA231LSVETDYTFP241LAEK
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 99 | SWISSPALM DBPTM CYSMODDB | Insertion domain in 60S ribosomal protein L10P | - |
cerebral cortex
(36430497)
|
GPS-Palm: 0.91
Deep-Palm: 0.97
|
| 206 | - | - |
Unknown
(32651440)
|
Deep-Palm: 0.90
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
2
LNCaP
Specificity: 0.500
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
2
Cerebral Cortex (Mass)
Specificity: 0.500
2/4 (50.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 27 | C → R | 0.001887 | SNP | Missense Mutation | UCEC |
| 44 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 48 | R → C | 0.002033 | SNP | Missense Mutation | LUSC |
| 273 | S → C | 0.003460 | SNP | Missense Mutation | CESC |