Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| F8VWB0 | SLC11A2 | Solute carrier family 11 member … | Homo sapiens (Human) | 149 aa |
Protein Details: F8VWB0 (SLC11A2)
Protein Information
| Accession | F8VWB0 |
|---|---|
| Protein Names | Solute carrier family 11 member 2 |
| Gene Symbol | SLC11A2 |
| Organism | Homo sapiens (Human) |
| Length | 149 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MVLGPEQKMS11DDSVSGDHGE21SASLGNINPA31YSNPSLSQSP41GDSEEYFATY
51-10051FNEKISIPEE61EYSCFSFRKL71WAFTGPGFLM81SIAYLDPGNI91ESDLQSGAVA
101-149101GFKLLWILLL111ATLVGLLLQR121LAARLGVVTG131LHLAEVCHRQ141YPKVPRVIL
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 64 | SWISSPALM DBPTM CYSMODDB | - |
HeLa
(29575903)
| - |
GPS-Palm: 0.88
Deep-Palm: 0.68
|
| 137 | - | - |
LNCaP
(31251020)
|
GPS-Palm: 0.81
Deep-Palm: 0.97
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
1
LNCaP
Specificity: 1.000
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 176 | S → C | 0.003460 | SNP | Missense Mutation | CESC |
| 245 | C → W | 0.001887 | SNP | Missense Mutation | UCEC |
| 408 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 489 | S → C | 0.001014 | SNP | Missense Mutation | BRCA |
| 544 | C → C | 0.001887 | SNP | Splice Region | UCEC |