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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
F8VWK8 CD63 Tetraspanin Homo sapiens (Human) 217 aa

Protein Details: F8VWK8 (CD63)

Protein Information
AccessionF8VWK8
Protein NamesTetraspanin
Gene SymbolCD63
OrganismHomo sapiens (Human)
Length217 aa
IsoformsNo isoforms
Related PMIDs 31251020 36430497 31251020 (mass) 32651440 (mass) 36430497 (mass)
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MAVEGGMKCV11KFLLYVLLLA21FCACAVGLIA31VGVGAQLVLS41QTIIQGATPG
51-10051SLLPVVIIAV61GVFLFLVAFV71GCCGACKENY81CLMITFAIFL91SLIMLVEVAA
101-150101AIAGYVFRDK111VMSEFNNNFR121QQMENYPKNN131HTASILDRMQ141ADFKCCGAAN
151-200151YTDWEKIPSM161SKNRVPDSCC171INVTVGCGIN181FNEKAIHKEG191CVEKIGGWLR
201-217201KNVLVVAAAA211LGIAFVE
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
9 - - -
Deep-Palm: 0.03
22 - - -
Deep-Palm: 0.89
24 - - -
GPS-Palm: 0.70
Deep-Palm: 0.93
72 - - -
GPS-Palm: 0.90
Deep-Palm: 0.91
73 - - -
GPS-Palm: 0.76
Deep-Palm: 0.91
76 - - -
Deep-Palm: 0.87
81 - - -
Deep-Palm: 0.83
145 - - -
GPS-Palm: 0.84
Deep-Palm: 0.76
146 - - -
GPS-Palm: 0.89
Deep-Palm: 0.84
169 SWISSPALM DBPTM CYSMODDB Tetraspanin family
HeLa (29575903)
cerebral cortex (36430497)
Deep-Palm: 0.18
170 SWISSPALM DBPTM CYSMODDB Tetraspanin family
HeLa (29575903)
cerebral cortex (36430497)
Deep-Palm: 0.33
177 SWISSPALM DBPTM CYSMODDB Tetraspanin family
HeLa (29575903)
cerebral cortex (36430497)
Deep-Palm: 0.26
191 - - -
GPS-Palm: 0.76
Deep-Palm: 0.93
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.800
4
LNCaP
Specificity: 0.444
4/4 (100.0%)
1
cerebral cortex
Specificity: 0.111
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
4
Cerebral Cortex (Mass)
Specificity: 0.444
4/4 (100.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine