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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
F8VWK9 OAS3 2'-5'-oligoadenylate synthetase 3 Homo sapiens (Human) 177 aa

Protein Details: F8VWK9 (OAS3)

Protein Information
AccessionF8VWK9
Protein Names2'-5'-oligoadenylate synthetase 3
Gene SymbolOAS3
OrganismHomo sapiens (Human)
Length177 aa
IsoformsNo isoforms
Related PMIDs 32944167
Database SourcesNo database sources
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MDLYSTPAAA11LDRFVARRLQ21PRKEFVEKAR31RALGALAAAL41RERGGRLGAA
51-10051APRVLKTVKG61GSSGRGTALK71GGCDSELVIF81LDCFKSYVDQ91RARRAEILSE
101-150101MRASLESWWQ111NPVPGLRLTF121PEQSVPGALQ131FRLTSVDLED141WMDVSLVPAF
151-177151NVLGEGFLDH161SRVGGKRSLG171TTQDFQF
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
73 - - -
Deep-Palm: 0.90
83 - - -
Deep-Palm: 0.96
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
2
PC3
Specificity: 1.000
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
94 R → C 0.002976 SNP Missense Mutation KIRC
257 G → C 0.001764 SNP Missense Mutation LUAD
328 C → C 0.002427 SNP Silent BLCA
340 W → C 0.002294 SNP Missense Mutation OV
443 R → C 0.001887 SNP Missense Mutation UCEC
449 C → del 0.003559 DEL In Frame Del KIRP
869 R → C 0.001887 SNP Missense Mutation UCEC
978 Y → C 0.002141 SNP Missense Mutation SKCM