Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| F8VX04 | SLC38A1 | Solute carrier family 38 member … | Homo sapiens (Human) | 503 aa |
Protein Details: F8VX04 (SLC38A1)
Protein Information
| Accession | F8VX04 |
|---|---|
| Protein Names | Solute carrier family 38 member 1 |
| Gene Symbol | SLC38A1 |
| Organism | Homo sapiens (Human) |
| Length | 503 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 32944167 |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MMHFKSGLEL11TELQNMTVPE21DDNISNDSND31FTEVENGQIN41SKFISDRESR
51-10051RSLTNSHLEK61KKCDEYIPGT71TSLGMSVFNL81SNAIMGSGIL91GLAFALANTG
101-150101ILLFLVLLTS111VTLLSIYSIN121LLLICSKETG131CMVYEKLGEQ141VFGTTGKFVI
151-200151FGATSLQNTG161AMLSYLFIVK171NELPSAIKFL181MGKEETFSAW191YVDGRVLVVI
201-250201VTFGIILPLC211LLKNLGYLGY221TSGFSLSCMV231FFLIVVIYKK241FQIPCIVPEL
251-300251NSTISANSTN261ADTCTPKYVT271FNSKTVYALP281TIAFAFVCHP291SVLPIYSELK
301-350301DRSQKKMQMV311SNISFFAMFV321MYFLTAIFGY331LTFYDNVQSD341LLHKYQSKDD
351-400351ILILTVRLAV361IVAVILTVPV371LFFTVRSSLF381ELAKKTKFNL391CRHTVVTCIL
401-450401LVVINLLVIF411IPSMKDIFGV421VGVTSANMLI431FILPSSLYLK441ITDQDGDKGT
451-500451QRIWLFLFLQ461FPVQPCWLSE471CIILLPAALS481LNMLKRKELI491ILCSLDSGFS
501-503501NLY
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 63 | - | - | - |
Deep-Palm: 0.59
|
|
| 125 | - | - | - |
GPS-Palm: 0.66
Deep-Palm: 0.92
|
|
| 131 | - | - | - |
GPS-Palm: 0.81
Deep-Palm: 0.86
|
|
| 210 | - | - | - |
GPS-Palm: 0.85
Deep-Palm: 0.97
|
|
| 228 | - | - | - |
Deep-Palm: 0.46
|
|
| 245 | - | - | - |
GPS-Palm: 0.74
Deep-Palm: 0.42
|
|
| 264 | - | - | - |
Deep-Palm: 0.20
|
|
| 288 | SWISSPALM DBPTM CYSMODDB | Transmembrane amino acid transporter protein |
HeLa
(29575903)
| - |
Deep-Palm: 0.53
|
| 391 | SWISSPALM DBPTM CYSMODDB | - |
HeLa
(29575903)
| - |
GPS-Palm: 0.88
Deep-Palm: 0.92
|
| 398 | - | - | - |
GPS-Palm: 0.69
Deep-Palm: 0.75
|
|
| 466 | - | - | - |
GPS-Palm: 0.71
Deep-Palm: 0.84
|
|
| 471 | - | - | - |
Deep-Palm: 0.84
|
|
| 493 | - | - | - |
GPS-Palm: 0.91
Deep-Palm: 0.37
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.571
4
PC3
Specificity: 0.571
4/4 (100.0%)
3
LNCaP
Specificity: 0.429
3/3 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 130 | G → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 264 | C → C | 0.002288 | SNP | Silent | STAD |
| 307 | M → Cfs*18 | 0.002288 | DEL | Frame Shift Del | STAD |
| 307 | M → Cfs*18 | 0.001887 | DEL | Frame Shift Del | UCEC |
| 376 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |