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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
F8W1A4 AK2 Adenylate kinase 2, mitochondrial (AK … Homo sapiens (Human) 232 aa

Protein Details: F8W1A4 (AK2)

Protein Information
Accession F8W1A4
Protein Names Adenylate kinase 2, mitochondrial (AK 2) (EC 2.7.4.3) (ATP-AMP transphosphorylase 2) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase)
Gene Symbol AK2
Organism Homo sapiens (Human)
Length 232 aa
Isoforms No isoforms
Related PMIDs 31251020 31382980
Database Sources No database sources
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.973
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
36
LNCaP cells
Specificity: 0.973
36/46 (78.3%)
1
U937 cells
Specificity: 0.027
1/1 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MAPSVPAAEP11EYPKGIRAVL21LGPPGAGKGT31QAPRLAENFC41VCHLATGDML
51-10051RAMVASGSEL61GKKLKATMDA71GKLVSDEMVV81ELIEKNLETP91LCKNGFLLDG
101-150101FPRTVRQAEM111LDDLMEKRKE121KLDSVIEFSI131PDSLLIRRIT141GRLIHPKSGR
151-200151SYHEEFNPPK161EPMKDDITGE171PLIRRSDDNE181KALKIRLQAY191HTQTTPLIEY
201-232201YRKRGIHSAI211DASQTPDVVF221ASILAAFSKA231TC
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
42 Prediction (Medium) - -
232 Prediction (High) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
174 R → C 0.002141 SNP Missense Mutation SKCM