Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| F8W1G6 | PCBP2 | Poly(rC) binding protein 2 | Homo sapiens (Human) | 202 aa |
Protein Details: F8W1G6 (PCBP2)
Protein Information
| Accession | F8W1G6 |
|---|---|
| Protein Names | Poly(rC) binding protein 2 |
| Gene Symbol | PCBP2 |
| Organism | Homo sapiens (Human) |
| Length | 202 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 32944167 36430497 31251020 (mass) 32651440 (mass) 36430497 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501GVIEGGLNVT11LTIRLLMHGK21EVGSIIGKKG31ESVKKMREES41GARINISEGN
51-10051CPERIITLAG61PTNAIFKAFA71MIIDKLEEDI81SSSMTNSTAA91SRPPVTLRLV
101-150101VPASQCGSLI111GKGGCKIKEI121RERRVSLFCS131GWSPTPELPM141IRLPWSPKVL
151-200151GLQIVQGLRS161RWQGICYPTQ171LSGPSLLLAF181HNPSLSVSNR191SAWSCWSPPR
201-202201RA
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 51 | SWISSPALM DBPTM CYSMODDB | KH domain K Homology domain, type 1 superfamily | - |
cerebral cortex
(36430497)
LNCaP
(31251020)
|
Deep-Palm: 0.96
|
| 106 | SWISSPALM DBPTM CYSMODDB | KH domain | - |
cerebral cortex
(36430497)
|
GPS-Palm: 0.90
Deep-Palm: 0.97
|
| 115 | - | - | - |
GPS-Palm: 0.90
Deep-Palm: 0.92
|
|
| 129 | - | - | - |
GPS-Palm: 0.83
Deep-Palm: 0.93
|
|
| 166 | - | - | - |
GPS-Palm: 0.71
Deep-Palm: 0.94
|
|
| 195 | - | - | - |
GPS-Palm: 0.92
Deep-Palm: 0.02
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.500
4
cerebral cortex
Specificity: 0.333
4/4 (100.0%)
3
PC3
Specificity: 0.250
3/3 (100.0%)
1
LNCaP
Specificity: 0.083
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
4
Cerebral Cortex (Mass)
Specificity: 0.333
4/4 (100.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 109 | C → W | 0.002545 | SNP | Missense Mutation | GBM |
| 148 | I → Cfs*9 | 0.002288 | DEL | Frame Shift Del | STAD |
| 305 | R → C | 0.002020 | SNP | Missense Mutation | PRAD |
| 314 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |