Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| F8W1G6 | PCBP2 | Poly(rC) binding protein 2 | Homo sapiens (Human) | 202 aa |
Protein Details: F8W1G6 (PCBP2)
Protein Information
| Accession | F8W1G6 |
|---|---|
| Protein Names | Poly(rC) binding protein 2 |
| Gene Symbol | PCBP2 |
| Organism | Homo sapiens (Human) |
| Length | 202 aa |
| Isoforms | No isoforms |
| Related PMIDs | 21076176 31251020 32944167 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.706
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
12
LNCaP cells
Specificity: 0.706
12/46 (26.1%)
3
PC3 cells
Specificity: 0.176
3/4 (75.0%)
2
Jurkat T cells
Specificity: 0.118
2/25 (8.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501GVIEGGLNVT11LTIRLLMHGK21EVGSIIGKKG31ESVKKMREES41GARINISEGN
51-10051CPERIITLAG61PTNAIFKAFA71MIIDKLEEDI81SSSMTNSTAA91SRPPVTLRLV
101-150101VPASQCGSLI111GKGGCKIKEI121RERRVSLFCS131GWSPTPELPM141IRLPWSPKVL
151-200151GLQIVQGLRS161RWQGICYPTQ171LSGPSLLLAF181HNPSLSVSNR191SAWSCWSPPR
201-202201RA
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 51 | CYSMODDB SWISSPALM DBPTM | KH domain | - |
| 106 | CYSMODDB SWISSPALM DBPTM Prediction (High) | KH domain | - |
| 115 | Prediction (High) | - | - |
| 129 | Prediction (Medium) | - | - |
| 166 | Prediction (Low) | - | - |
| 195 | Prediction (High) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 109 | C → W | 0.002545 | SNP | Missense Mutation | GBM |
| 148 | I → Cfs*9 | 0.002288 | DEL | Frame Shift Del | STAD |
| 305 | R → C | 0.002020 | SNP | Missense Mutation | PRAD |
| 314 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |