Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| F8W785 | GOLIM4 | Golgi integral membrane protein 4 | Homo sapiens (Human) | 668 aa |
Protein Details: F8W785 (GOLIM4)
Protein Information
| Accession | F8W785 |
|---|---|
| Protein Names | Golgi integral membrane protein 4 |
| Gene Symbol | GOLIM4 |
| Organism | Homo sapiens (Human) |
| Length | 668 aa |
| Isoforms | No isoforms |
| Related PMIDs | 19801377 22496122 29575903 31251020 31382980 32944167 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.364
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
4
PC3 cells
Specificity: 0.364
4/4 (100.0%)
2
DU145 cells
Specificity: 0.182
2/2 (100.0%)
2
LNCaP cells
Specificity: 0.182
2/46 (4.3%)
1
U937 cells
Specificity: 0.091
1/1 (100.0%)
1
HeLa cells
Specificity: 0.091
1/1 (100.0%)
1
Endothelial cells
Specificity: 0.091
1/2 (50.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MGNGMCSRKQ11KRIFQTLLLL21TVVFGFLYGA31MLYYELQTQL41RKAEAVALKY
51-10051QQHQESLSAQ61LQVVYEHRSR71LEKSLQKERL81EHKKAKEDFL91VYKLEAQETL
101-150101NKGRQDSNSR111YSALNVQHQM121LKSQHEELKK131QHSDLEEEHR141KQGEDFSRTF
151-200151NDHKQKYLQL161QQEKEQELSK171LKETVYNLRE181ENRQLRKAHQ191DIHTQLQDVK
201-250201TQVAEYKQLK211DTLNRIPSLR221KPDPAEQQNV231TQVAHSPQGY241NTAREKPTRE
251-300251VQEVSRNNDV261WQNHEAVPGR271AEDTKLYAPT281HKEAEFQAPP291EPIQQEVERR
301-350301EPEEHQVEEE311HRKALEEEEM321EQVGQAEHLE331EEHDPSPEEQ341DREWKEQHEQ
351-400351REAANLLEGH361ARAEVYPSAK371PMIKFQSPYE381EQLEQQRLAV391QQVEEAQQLR
401-450401EHQEALHQQR411LQGHLLRQQE421QQQQQVAREM431ALQRQAELEE441GRPQHQEQLR
451-500451QQAHYDAMDN461DIVQGAEDQG471IQGEEGAYER481DNQHQDEAEG491DPGNRHEPRE
501-550501QGPREADPES511EADRAAVEDI521NPADDPNNQG531EDEFEEAEQV541REENLPDENE
551-600551EQKQSNQKQE561NTEVEEHLVM571AGNPDQQEDN581VDEQYQEEAE591EEVQEDLTEE
601-650601KKRELEHNAE611ETYGENDENT621DDKNNDGEEQ631EVRDDNRPKG641REEHYEEEEE
651-668651EEEDGAAVAE661KSHRRAEM
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 6 | CYSMODDB SWISSPALM DBPTM Prediction (High) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 123 | S → delinsNTRHILFC | 0.001887 | INS | Splice Region | UCEC |
| 305 | Y → C | 0.002033 | SNP | Missense Mutation | LUSC |
| 327 | R → C | 0.002288 | SNP | Missense Mutation | STAD |
| 521 | G → C | 0.002033 | SNP | Missense Mutation | LUSC |
| 527 | R → C | 0.002288 | SNP | Missense Mutation | STAD |
| 527 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |