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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
F8WBE5 TFRC Transferrin receptor Homo sapiens (Human) 81 aa

Protein Details: F8WBE5 (TFRC)

Protein Information
AccessionF8WBE5
Protein NamesTransferrin receptor
Gene SymbolTFRC
OrganismHomo sapiens (Human)
Length81 aa
IsoformsNo isoforms
Related PMIDs 19801377 29575903 31251020 32944167 36430497
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MMDQARSAFS11NLFGGEPLSY21TRFSLARQVD31GDNSHVEMKL41AVDEEENADN
51-8151NTKANVTKPK61RCSGSICYGT71IAVIVFFLIG81C
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
62 SWISSPALM DBPTM CYSMODDB - - -
GPS-Palm: 0.83
Deep-Palm: 0.55
67 SWISSPALM DBPTM CYSMODDB - - -
GPS-Palm: 0.80
Deep-Palm: 0.60
81 - - -
GPS-Palm: 0.97
Deep-Palm: 0.03
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.333
4
LNCaP
Specificity: 0.333
4/4 (100.0%)
4
PC3
Specificity: 0.333
4/4 (100.0%)
2
HeLa cell
Specificity: 0.167
2/2 (100.0%)
1
cerebral cortex
Specificity: 0.083
1/1 (100.0%)
1
DU145 cell
Specificity: 0.083
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
152 Y → C 0.001969 SNP Missense Mutation HNSC
174 R → C 0.007299 SNP Missense Mutation READ
174 R → C 0.002141 SNP Missense Mutation SKCM
174 R → C 0.003774 SNP Missense Mutation UCEC
321 F → delinsLEYVALILIC 0.002294 INS In Frame Ins OV
338 S → C 0.001764 SNP Missense Mutation LUAD
646 R → C 0.002427 SNP Missense Mutation BLCA
719 R → C 0.001887 SNP Missense Mutation UCEC
719 R → C 0.005435 SNP Missense Mutation ESCA
719 R → C 0.003460 SNP Missense Mutation CESC