Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| F8WEJ5 | ASNS | Asparagine synthetase [glutamine-hydrolyzing] (EC 6.3.5.4) … | Homo sapiens (Human) | 401 aa |
Protein Details: F8WEJ5 (ASNS)
Protein Information
| Accession | F8WEJ5 |
|---|---|
| Protein Names | Asparagine synthetase [glutamine-hydrolyzing] (EC 6.3.5.4) (Glutamine-dependent asparagine synthetase) |
| Gene Symbol | ASNS |
| Organism | Homo sapiens (Human) |
| Length | 401 aa |
| Isoforms | No isoforms |
| Related PMIDs | 19801377 29575903 31251020 32944167 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.821
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
32
LNCaP cells
Specificity: 0.821
32/46 (69.6%)
4
PC3 cells
Specificity: 0.103
4/4 (100.0%)
2
DU145 cells
Specificity: 0.051
2/2 (100.0%)
1
HeLa cells
Specificity: 0.026
1/1 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MCGIWALFGS11DDCLSVQCLS21AMKIAHRGPD31AFRFENVNGY41TNCCFGFHRL
51-10051AVVDPLFGMQ61PIRVKKYPYL71WLCYNGEIYN81HKKMQQHFEF91EYQTKVDGEI
101-150101ILHLYDKGGI111EQTICMLDGV121FAFVLLDTAN131KKVFLGRDTY141GVRPLFKAMT
151-200151EDGFLAVCSE161AKGLVTLKHS171ATPFLKVEPF181LPGHYEVLDL191KPNGKVASVE
201-250201MVKYHHCRDV211PLHALYDNVE221KLFPGFEIET231VKNNLRILFN241NAVKKRLMTD
251-300251RRIGCLLSGG261LDSSLVAATL271LKQLKEAQVQ281YPLQTFAIGM291EDSPDLLAAR
301-350301KVADHIGSEH311YEVLFNSEEG321IQALDEVIFS331LETYDITTVR341ASVGMYLISK
351-400351YIRKNTDSVV361IFSGEGSDEL371TQGYIYFHKD381WRGRKKNCFV391CQKQNSWCFC
401-401401L
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 2 | Prediction (High) | - | - |
| 13 | Prediction (Low) | - | - |
| 18 | Prediction (Low) | - | - |
| 115 | Prediction (Low) | - | - |
| 158 | Prediction (Low) | - | - |
| 255 | Prediction (High) | - | - |
| 388 | Prediction (Medium) | - | - |
| 391 | Prediction (Low) | - | - |
| 398 | Prediction (High) | - | - |
| 400 | Prediction (High) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 44 | C → C | 0.001887 | SNP | Silent | UCEC |
| 185 | Y → C | 0.002033 | SNP | Missense Mutation | LUSC |
| 340 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 519 | R → C | 0.003460 | SNP | Missense Mutation | CESC |
| 548 | S → C | 0.003460 | SNP | Missense Mutation | CESC |