Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| G3V0E5 | TFRC; hCG_22086 | Transferrin receptor protein 1 | Homo sapiens (Human) | 679 aa |
Protein Details: G3V0E5 (TFRC)
Protein Information
| Accession | G3V0E5 |
|---|---|
| Protein Names | Transferrin receptor protein 1 |
| Gene Symbol | TFRC; hCG_22086 |
| Organism | Homo sapiens (Human) |
| Length | 679 aa |
| Isoforms | No isoforms |
| Related PMIDs | 19137006 19801377 21076176 22496122 29575903 31251020 32651440 32944167 36430497 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.676
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
46
LNCaP cells
Specificity: 0.676
46/46 (100.0%)
13
Jurkat T cells
Specificity: 0.191
13/25 (52.0%)
4
PC3 cells
Specificity: 0.059
4/4 (100.0%)
2
DU145 cells
Specificity: 0.029
2/2 (100.0%)
1
HeLa cells
Specificity: 0.015
1/1 (100.0%)
1
Endothelial cells
Specificity: 0.015
1/2 (50.0%)
1
Cerebral cortex
Specificity: 0.015
1/4 (25.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MIGYLGYCKG11VEPKTECERL21AGTESPVREE31PGEDFPAARR41LYWDDLKRKL
51-10051SEKLDSTDFT61GTIKLLNENS71YVPREAGSQK81DENLALYVEN91QFREFKLSKV
101-150101WRDQHFVKIQ111VKDSAQNSVI121IVDKNGRLVY131LVENPGGYVA141YSKAATVTGK
151-200151LVHANFGTKK161DFEDLYTPVN171GSIVIVRAGK181ITFAEKVANA191ESLNAIGVLI
201-250201YMDQTKFPIV211NAELSFFGHA221HLGTGDPYTP231GFPSFNHTQF241PPSRSSGLPN
251-300251IPVQTISRAA261AEKLFGNMEG271DCPSDWKTDS281TCRMVTSESK291NVKLTVSNVL
301-350301KEIKILNIFG311VIKGFVEPDH321YVVVGAQRDA331WGPGAAKSGV341GTALLLKLAQ
351-400351MFSDMVLKDG361FQPSRSIIFA371SWSAGDFGSV381GATEWLEGYL391SSLHLKAFTY
401-450401INLDKAVLGT411SNFKVSASPL421LYTLIEKTMQ431NVKHPVTGQF441LYQDSNWASK
451-500451VEKLTLDNAA461FPFLAYSGIP471AVSFCFCEDT481DYPYLGTTMD491TYKELIERIP
501-550501ELNKVARAAA511EVAGQFVIKL521THDVELNLDY531ERYNSQLLSF541VRDLNQYRAD
551-600551IKEMGLSLQW561LYSARGDFFR571ATSRLTTDFG581NAEKTDRFVM591KKLNDRVMRV
601-650601EYHFLSPYVS611PKESPFRHVF621WGSGSHTLPA631LLENLKLRKQ641NNGAFNETLF
651-679651RNQLALATWT661IQGAANALSG671DVWDIDNEF
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 8 | Prediction (High) | - | - |
| 272 | CYSMODDB SWISSPALM DBPTM | - | - |
| 282 | CYSMODDB SWISSPALM DBPTM | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 152 | Y → C | 0.001969 | SNP | Missense Mutation | HNSC |
| 174 | R → C | 0.007299 | SNP | Missense Mutation | READ |
| 174 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |
| 174 | R → C | 0.003774 | SNP | Missense Mutation | UCEC |
| 321 | F → delinsLEYVALILIC | 0.002294 | INS | In Frame Ins | OV |
| 338 | S → C | 0.001764 | SNP | Missense Mutation | LUAD |
| 646 | R → C | 0.002427 | SNP | Missense Mutation | BLCA |
| 719 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 719 | R → C | 0.005435 | SNP | Missense Mutation | ESCA |
| 719 | R → C | 0.003460 | SNP | Missense Mutation | CESC |