Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| G3V476 | RHOJ | Ras homolog family member J | Homo sapiens (Human) | 178 aa |
Protein Details: G3V476 (RHOJ)
Protein Information
| Accession | G3V476 |
|---|---|
| Protein Names | Ras homolog family member J |
| Gene Symbol | RHOJ |
| Organism | Homo sapiens (Human) |
| Length | 178 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MNCKEGTDSS11CGCRGNDEKK21MLKCVVVGDG31AVGKTCLLMS41YANDAFPEEY
51-10051VPTVFDHYAV61TVTVGGKQHL71LGLYDTAGQE81DYNQLRPLSY91PNTDVFLICF
101-150101SVVNPASYHN111VQEEWVPELK121DCMPHVPYVL131IGTQIDLRDD141PKTLARLLYM
151-178151KEKPLTYEHG161VKLAKAVQSD171LNFILNVC
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 3 | - | - | - |
GPS-Palm: 0.84
Deep-Palm: 0.01
|
|
| 11 | - | - | - |
Deep-Palm: 0.02
|
|
| 13 | P-loop containing nucleoside triphosphate hydrolase | - | - |
GPS-Palm: 0.67
Deep-Palm: 0.03
|
|
| 24 | SWISSPALM DBPTM CYSMODDB | Ras family P-loop containing nucleoside triphosphate hydrolase Small GTPase | - |
cerebral cortex
(36430497)
|
GPS-Palm: 0.66
Deep-Palm: 0.97
|
| 36 | P-loop containing nucleoside triphosphate hydrolase Small GTPase Rho Small GTPase Transforming protein P21 ras signature | - | - |
Deep-Palm: 0.93
|
|
| 99 | - | - | - |
Deep-Palm: 0.75
|
|
| 122 | - | - | - |
Deep-Palm: 0.75
|
|
| 178 | - | - | - |
GPS-Palm: 0.97
Deep-Palm: 0.03
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
2
LNCaP
Specificity: 1.000
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 11 | C → C | 0.002288 | SNP | Silent | STAD |
| 11 | C → C | 0.001887 | SNP | Silent | UCEC |
| 24 | C → C | 0.002506 | SNP | Silent | COAD |
| 37 | L → Cfs*2 | 0.001764 | DEL | Frame Shift Del | LUAD |
| 108 | Y → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 172 | Y → C | 0.002288 | SNP | Missense Mutation | STAD |