Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
G3XAC1 SLC26A6; hCG_1999608 Solute carrier family 26 member … Homo sapiens (Human) 651 aa

Protein Details: G3XAC1 (SLC26A6)

Protein Information
Accession G3XAC1
Protein Names Solute carrier family 26 member 6 (Solute carrier family 26, member 6, isoform CRA_i)
Gene Symbol SLC26A6; hCG_1999608
Organism Homo sapiens (Human)
Length 651 aa
Isoforms No isoforms
Related PMIDs 29575903 31251020 32944167
Database Sources CysModDB dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.900
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
36
LNCaP cells
Specificity: 0.900
36/46 (78.3%)
4
PC3 cells
Specificity: 0.100
4/4 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MGLADASGPR11DTQALLSATQ21AMDLRRRDYH31MERPLLNQEH41LEELGRWGSA
51-10051PRTHQWRTWL61QCSRARAYAL71LLQHLPVLVW81LPRYPVRDWL91LGDLLSGLSV
101-150101AIMQLPQGLA111YALLAGLPPV121FGLYSSFYPV131FIYFLFGTSR141HISVVLEVCW
151-200151KLPQSKVGTV161VTAAVAGVVL171VVVKLLNDKL181QQQLPMPIPG191ELLTLIGATG
201-250201ISYGMGLKHR211FEVDVVGNIP221AGLVPPVAPN231TQLFSKLVGS241AFTIAVVGFA
251-300251IAISLGKIFA261LRHGYRVDSN271QELVALGLSN281LIGGIFQCFP291VSCSMSRSLV
301-350301QESTGGNSQV311AGAISSLFIL321LIIVKLGELF331HDLPKAVLAA341IIIVNLKGML
351-400351RQLSDMRSLW361KANRADLLIW371LVTFTATILL381NLDLGLVVAV391IFSLLLVVVR
401-450401TQMPHYSVLG411QVPDTDIYRD421VAEYSEAKEV431RGVKVFRSSA441TVYFANAEFY
451-500451SDALKQRCGV461DVDFLISQKK471KLLKKQEQLK481LKQLQKEEKL491RKQAASPKGA
501-550501SVSINVNTSL511EDMRSNNVED521CKMMVSSGDK531MEDATANGQE541DSKAPDGSTL
551-600551KALGLPQPDF561HSLILDLGAL571SFVDTVCLKS581LKNIFHDFRE591IEVEVYMAAC
601-650601HSPVVSQLEA611GHFFDASITK621KHLFASVHDA631VTFALQHPRP641VPDSPVSVTR
651-651651L
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
62 Experimental CYSMODDB SWISSPALM DBPTM Prediction (Low) - 29575903
149 Prediction (Low) - -
288 Prediction (Low) - -
293 Prediction (Low) - -
458 Prediction (Low) - -
521 Prediction (Low) - -
577 Prediction (High) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
87 R → C 0.001764 SNP Missense Mutation LUAD
97 G → C 0.001887 SNP Missense Mutation UCEC
531 Y → C 0.002506 SNP Missense Mutation COAD
544 R → C 0.002033 SNP Missense Mutation LUSC
544 R → C 0.002141 SNP Missense Mutation SKCM
683 T → _V684insHYSECACEGGF 0.005435 INS In Frame Ins ESCA
400* C → ? 0.002288 SNP Nonsense Mutation STAD