Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
G5E895 Akr1b10 aldose reductase (EC 1.1.1.21) (Aldehyde … Mus musculus (Mouse) 316 aa

Protein Details: G5E895 (Akr1b10)

Protein Information
AccessionG5E895
Protein Namesaldose reductase (EC 1.1.1.21) (Aldehyde reductase)
Gene SymbolAkr1b10
OrganismMus musculus (Mouse)
Length316 aa
IsoformsNo isoforms
Related PMIDs 29660268 35477839
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MAAFVTLLTG11AKMPIVGLGT21WKSPPAKVRE31AVKVAIDAGY41RHIDCAYVYQ
51-10051NESEVGEAIQ61EKIQEKAVKR71EDLFIVSKLW81STFFEKSLVK91KAFQNTLSDL
101-150101KLDYLDLYLI111HWPQGFQSGN121VFLPTDDKGS131ILSSKYTFLD141AWEAMEELVD
151-200151QGLVKALGVS161NFNHFQIERL171LNKPGLKHKP181VTNQVECHPY191LTQEKLIQYC
201-250201HSKGITITAY211SPLGSPDRPS221AKPEDPLLLE231IPKIKEIAAK241HKRTAAQVLI
251-300251RFHIERNVVV261IPKSVTPSRI271QENIQVFDFQ281LSEEDMAAIL291SFNRNWRACG
301-316301LFAASHNEDF311PFHAEY
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
45 NADP-dependent oxidoreductase domain NADP-dependent oxidoreductase domain superfamily Aldo-keto reductase - -
Deep-Palm: 0.63
187 - - -
Deep-Palm: 0.31
200 - - -
Deep-Palm: 0.62
299 SWISSPALM DBPTM CYSMODDB -
Forebrain (28680068)
-
GPS-Palm: 0.94
Deep-Palm: 0.48
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.667
2
Testis
Specificity: 0.667
2/2 (100.0%)
1
Brain
Specificity: 0.333
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine