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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
G8HBB1 GRIA2 AMPA-selective glutamate receptor 2 Homo sapiens (Human) 72 aa

Protein Details: G8HBB1 (GRIA2)

Protein Information
AccessionG8HBB1
Protein NamesAMPA-selective glutamate receptor 2
Gene SymbolGRIA2
OrganismHomo sapiens (Human)
Length72 aa
IsoformsNo isoforms
Related PMIDs 26876311 36430497
Database SourcesNo database sources
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501TMKVGGNLDS11KGYGIATPKG21SSLRNAVNLA31VLKLNEQGLL41DKLKNKWWYD
51-7251KGECGAKDSG61SKEKTSALSL71SN
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
54 - - -
GPS-Palm: 0.70
Deep-Palm: 0.92
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.800
4
cerebral cortex
Specificity: 0.800
4/4 (100.0%)
1
frontal cortex
Specificity: 0.200
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
104 C → C 0.001764 SNP Silent LUAD
104 C → C 0.002033 SNP Silent LUSC
206 R → C 0.001969 SNP Missense Mutation HNSC
211 C → Y 0.002288 SNP Missense Mutation STAD
242 F → C 0.001887 SNP Missense Mutation UCEC
273 F → C 0.001887 SNP Missense Mutation UCEC
285 Y → C 0.001887 SNP Missense Mutation UCEC
295 Y → C 0.002141 SNP Missense Mutation SKCM
312 R → C 0.001764 SNP Missense Mutation LUAD
312 R → C 0.002020 SNP Missense Mutation PRAD
424 S → C 0.001764 SNP Missense Mutation LUAD
426 Y → C 0.001887 SNP Missense Mutation UCEC
441 R → C 0.002506 SNP Missense Mutation COAD
522 S → C 0.002976 SNP Missense Mutation KIRC
610 C → W 0.001764 SNP Missense Mutation LUAD
610 C → C 0.001887 SNP Silent UCEC
620 R → C 0.007299 SNP Missense Mutation READ
668 Y → C 0.002288 SNP Missense Mutation STAD
679 F → C 0.001887 SNP Missense Mutation UCEC
794 C → C 0.003774 SNP Silent UCEC
549* C → ? 0.003559 SNP Nonsense Mutation KIRP