Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| G8JLH6 | CD9 | Tetraspanin | Homo sapiens (Human) | 251 aa |
Protein Details: G8JLH6 (CD9)
Protein Information
| Accession | G8JLH6 |
|---|---|
| Protein Names | Tetraspanin |
| Gene Symbol | CD9 |
| Organism | Homo sapiens (Human) |
| Length | 251 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 36430497 31251020 (mass) 32651440 (mass) 36430497 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MPVKGGTKCI11KYLLFGFNFI21FWLAGIAVLA31IGLWLRFDSQ41TKSIFEQETN
51-10051NNNSSFYTGV61YILIGAGALM71MLVGFLGCCG81AVQESQCMLG91LATKRTMFPP
101-150101FLEDHVCFFS111LNPQFFGFLL121VIFAIEIAAA131IWGYSHKDEV141IKEVQEFYKD
151-200151TYNKLKTKDE161PQRETLKAIH171YALNCCGLAG181GVEQFISDIC191PKKDVLETFT
201-250201VKSCPDAIKE211VFDNKFHIIG221AVGIGIAVVM231IFGMIFSMIL241CCAIRRNREM
251-251251V
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 9 | - | - | - |
GPS-Palm: 0.88
Deep-Palm: 0.02
|
|
| 78 | - | - | - |
GPS-Palm: 0.87
Deep-Palm: 0.98
|
|
| 79 | - | - | - |
GPS-Palm: 0.84
Deep-Palm: 0.97
|
|
| 87 | - | - | - |
GPS-Palm: 0.80
Deep-Palm: 0.96
|
|
| 107 | - | - | - |
Deep-Palm: 0.40
|
|
| 175 | - |
HeLa
(29575903)
|
LNCaP
(31251020)
cerebral cortex
(36430497)
|
GPS-Palm: 0.90
Deep-Palm: 0.97
|
|
| 176 | - |
HeLa
(29575903)
|
LNCaP
(31251020)
cerebral cortex
(36430497)
|
GPS-Palm: 0.91
Deep-Palm: 0.97
|
|
| 190 | SWISSPALM DBPTM CYSMODDB | - | - |
LNCaP
(31251020)
cerebral cortex
(36430497)
|
GPS-Palm: 0.83
Deep-Palm: 0.88
|
| 204 | - | - |
cerebral cortex
(36430497)
|
GPS-Palm: 0.84
Deep-Palm: 0.74
|
|
| 241 | - | - | - |
GPS-Palm: 0.96
Deep-Palm: 0.03
|
|
| 242 | - | - | - |
GPS-Palm: 0.96
Deep-Palm: 0.03
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.500
4
LNCaP
Specificity: 0.308
4/4 (100.0%)
4
cerebral cortex
Specificity: 0.308
4/4 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.800
4
Cerebral Cortex (Mass)
Specificity: 0.308
4/4 (100.0%)
1
LNCaP cells (Mass)
Specificity: 0.077
1/4 (25.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 12 | Y → C | 0.002141 | SNP | Missense Mutation | SKCM |
| 222 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 152* | C → ? | 0.001887 | SNP | Nonsense Mutation | UCEC |
| 78* | C → ? | 0.001887 | SNP | Nonsense Mutation | UCEC |