Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| H0Y3X1 | HMCN2 | Hemicentin 2 | Homo sapiens (Human) | 309 aa |
Protein Details: H0Y3X1 (HMCN2)
Protein Information
| Accession | H0Y3X1 |
|---|---|
| Protein Names | Hemicentin 2 |
| Gene Symbol | HMCN2 |
| Organism | Homo sapiens (Human) |
| Length | 309 aa |
| Isoforms | No isoforms |
| Related PMIDs | No related PMIDs |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MPGQLFVGST11QRFFQGGLPS21FLRCNHSIQY31NAARGPQPQL41VQHLRASAIS
51-10051SAFDPEAEAL61RFQLATALQA71EENEVGCPEG81FELDSQGAFC91VDVDECAWDA
101-150101HLCREGQRCV111NLLGSYRCLP121DCGPGFRVAD131GAGCEDVDEC141LEGLDDCHYN
151-200151QLCENTPGGH161RCSCPRGYRM171QGPSLPCLDV181NECLQLPKAC191AYQCHNLQGS
201-250201YRCLCPPGQT211LLRDGKACTS221LERNGQNVTT231VSHRGPLLPW241LRPWASIPGT
251-300251SYHAWVSLRP261GPMALSSVGR271AWCPPGFIRQ281NGVCTDLDEC291RVRNLCQHAC
301-309301RNTEGSYQC
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 24 | Green fluorescent protein G2 nidogen/fibulin G2F | - | - |
GPS-Palm: 0.69
Deep-Palm: 0.61
|
|
| 77 | - | - | - |
Deep-Palm: 0.74
|
|
| 90 | - | - | - |
Deep-Palm: 0.08
|
|
| 96 | - | - | - |
Deep-Palm: 0.03
|
|
| 103 | - | - | - |
Deep-Palm: 0.03
|
|
| 109 | - | - | - |
Deep-Palm: 0.06
|
|
| 118 | - | - | - |
GPS-Palm: 0.70
Deep-Palm: 0.63
|
|
| 122 | - | - | - |
GPS-Palm: 0.92
Deep-Palm: 0.66
|
|
| 134 | - | - | - |
Deep-Palm: 0.23
|
|
| 140 | - | - | - |
Deep-Palm: 0.04
|
|
| 147 | - | - | - |
Deep-Palm: 0.03
|
|
| 153 | - | - | - |
Deep-Palm: 0.02
|
|
| 162 | - | - | - |
Deep-Palm: 0.03
|
|
| 164 | - | - | - |
Deep-Palm: 0.06
|
|
| 177 | - | - | - |
GPS-Palm: 0.69
Deep-Palm: 0.34
|
|
| 183 | - | - | - |
Deep-Palm: 0.12
|
|
| 190 | - | - | - |
GPS-Palm: 0.68
Deep-Palm: 0.08
|
|
| 194 | - | - | - |
Deep-Palm: 0.05
|
|
| 203 | SWISSPALM DBPTM CYSMODDB | Calcium-binding EGF domain | - | - |
Deep-Palm: 0.36
|
| 205 | SWISSPALM DBPTM CYSMODDB | Calcium-binding EGF domain | - | - |
GPS-Palm: 0.70
Deep-Palm: 0.42
|
| 218 | - | - | - |
GPS-Palm: 0.87
Deep-Palm: 0.78
|
|
| 273 | - | - | - |
GPS-Palm: 0.81
Deep-Palm: 0.69
|
|
| 284 | - | - | - |
Deep-Palm: 0.15
|
|
| 290 | - | - | - |
Deep-Palm: 0.09
|
|
| 296 | - | - | - |
Deep-Palm: 0.04
|
|
| 300 | - | - | - |
Deep-Palm: 0.03
|
|
| 309 | - | - | - |
GPS-Palm: 0.92
Deep-Palm: 0.01
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 3436 | C → C | 0.001887 | SNP | Silent | UCEC |
| 4950 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 5006 | R → C | 0.003460 | SNP | Missense Mutation | CESC |
| 5038 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |