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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
H0Y5F3 FLNA Filamin A Homo sapiens (Human) 232 aa

Protein Details: H0Y5F3 (FLNA)

Protein Information
AccessionH0Y5F3
Protein NamesFilamin A
Gene SymbolFLNA
OrganismHomo sapiens (Human)
Length232 aa
IsoformsNo isoforms
Related PMIDs 29575903 31251020 32944167 36430497
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501XKYVICVRFG11GEHVPNSPFQ21VTALAGDQPS31VQPPLRSQQL41APQYTYAQGG
51-10051QQTWAPERPL61VGVNGLDVTS71LRPFDLVIPF81TIKKGEITGE91VRMPSGKVAQ
101-150101PTITDNKDGT111VTVRYAPSEA121GLHEMDIRYD131NMHIPGSPLQ141FYVDYVNCGH
151-200151VTAYGPGLTH161GVVNKPATFT171VNTKDAGEGD181DSMRMSHLKV191GSAADIPINI
201-232201SETDLSLLTA211TVVPPSGREE221PCLLKRLRNG231HV
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
6 SWISSPALM DBPTM CYSMODDB Immunoglobulin-like fold Immunoglobulin E-set Filamin/ABP280 repeat-like - -
GPS-Palm: 0.94
Deep-Palm: 0.03
148 - - -
Deep-Palm: 0.14
222 - - -
GPS-Palm: 0.94
Deep-Palm: 0.18
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.333
4
PC3
Specificity: 0.333
4/4 (100.0%)
4
cerebral cortex
Specificity: 0.333
4/4 (100.0%)
3
LNCaP
Specificity: 0.250
3/3 (100.0%)
1
HeLa cell
Specificity: 0.083
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine