Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| H0Y5F5 | PABPC4 | Polyadenylate-binding protein (PABP) | Homo sapiens (Human) | 550 aa |
Protein Details: H0Y5F5 (PABPC4)
Protein Information
| Accession | H0Y5F5 |
|---|---|
| Protein Names | Polyadenylate-binding protein (PABP) |
| Gene Symbol | PABPC4 |
| Organism | Homo sapiens (Human) |
| Length | 550 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501XNVFIKNLDK11SIDNKALYDT21FSAFGNILSC31KVVCDENGSK41GYAFVHFETQ
51-10051EAADKAIEKM61NGMLLNDRKV71FVGRFKSRKE81REAELGAKAK91EFTNVYIKNF
101-150101GEEVDDESLK111ELFSQFGKTL121SVKVMRDPNG131KSKGFGFVSY141EKHEDANKAV
151-200151EEMNGKEISG161KIIFVGRAQK171KVERQAELKR181KFEQLKQERI191SRYQGVNLYI
201-250201KNLDDTIDDE211KLRKEFSPFG221SITSAKVMLE231DGRSKGFGFV241CFSSPEEATK
251-300251AVTEMNGRIV261GSKPLYVALA271QRKEERKAHL281TNQYMQRVAG291MRALPANAIL
301-350301NQFQPAAGGY311FVPAVPQAQG321RPPYYTPNQL331AQMRPNPRWQ341QGGRPQGFQG
351-400351MPSAIRQSGP361RPTLRHLAPT371GNAPASRGLP381TTTQRVGSEC391PDRLAMDFGG
401-450401AGAAQQGLTD411SCQSGGVPTA421VQNLAPRAAV431AAAAPRAVAP441YKYASSVRSP
451-500451HPAIQPLQPL461TASMLAAAPP471QEQKQMLGER481LFPLIQTMHS491NLAGKITGML
501-550501LEIDNSELLH511MLESPESLRS521KVDEAVAVLQ531AHHAKKEAAQ541KVGAVAAATS
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 30 | SWISSPALM DBPTM CYSMODDB | RNA BINDING PROTEIN Nucleotide-binding alpha-beta plait domain superfamily RNA recognition motif RNA-binding domain superfamily RNA recognition motif domain | - |
Unknown
(32651440)
|
GPS-Palm: 0.79
Deep-Palm: 0.70
|
| 34 | RNA BINDING PROTEIN Nucleotide-binding alpha-beta plait domain superfamily RNA-binding domain superfamily RNA recognition motif domain | - | - |
GPS-Palm: 0.69
Deep-Palm: 0.18
|
|
| 241 | SWISSPALM DBPTM CYSMODDB | RNA recognition motif | - | - |
GPS-Palm: 0.82
Deep-Palm: 0.88
|
| 390 | - | - | - |
Deep-Palm: 0.93
|
|
| 412 | - | - | - |
Deep-Palm: 0.96
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
3
LNCaP
Specificity: 1.000
3/3 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 171 | G → C | 0.002294 | SNP | Missense Mutation | OV |
| 265 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |
| 436 | R → C | 0.002288 | SNP | Missense Mutation | STAD |
| 463 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |
| 509 | R → C | 0.002427 | SNP | Missense Mutation | BLCA |
| 509 | R → C | 0.005435 | SNP | Missense Mutation | ESCA |
| 530 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |