Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| H0Y5F5 | PABPC4 | Polyadenylate-binding protein (PABP) | Homo sapiens (Human) | 550 aa |
Protein Details: H0Y5F5 (PABPC4)
Protein Information
| Accession | H0Y5F5 |
|---|---|
| Protein Names | Polyadenylate-binding protein (PABP) |
| Gene Symbol | PABPC4 |
| Organism | Homo sapiens (Human) |
| Length | 550 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
35
LNCaP cells
Specificity: 1.000
35/46 (76.1%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501XNVFIKNLDK11SIDNKALYDT21FSAFGNILSC31KVVCDENGSK41GYAFVHFETQ
51-10051EAADKAIEKM61NGMLLNDRKV71FVGRFKSRKE81REAELGAKAK91EFTNVYIKNF
101-150101GEEVDDESLK111ELFSQFGKTL121SVKVMRDPNG131KSKGFGFVSY141EKHEDANKAV
151-200151EEMNGKEISG161KIIFVGRAQK171KVERQAELKR181KFEQLKQERI191SRYQGVNLYI
201-250201KNLDDTIDDE211KLRKEFSPFG221SITSAKVMLE231DGRSKGFGFV241CFSSPEEATK
251-300251AVTEMNGRIV261GSKPLYVALA271QRKEERKAHL281TNQYMQRVAG291MRALPANAIL
301-350301NQFQPAAGGY311FVPAVPQAQG321RPPYYTPNQL331AQMRPNPRWQ341QGGRPQGFQG
351-400351MPSAIRQSGP361RPTLRHLAPT371GNAPASRGLP381TTTQRVGSEC391PDRLAMDFGG
401-450401AGAAQQGLTD411SCQSGGVPTA421VQNLAPRAAV431AAAAPRAVAP441YKYASSVRSP
451-500451HPAIQPLQPL461TASMLAAAPP471QEQKQMLGER481LFPLIQTMHS491NLAGKITGML
501-550501LEIDNSELLH511MLESPESLRS521KVDEAVAVLQ531AHHAKKEAAQ541KVGAVAAATS
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 30 | CYSMODDB SWISSPALM DBPTM Prediction (Medium) | RNA recognition motif | - |
| 34 | Prediction (Low) | - | - |
| 241 | CYSMODDB SWISSPALM DBPTM Prediction (Medium) | RNA recognition motif | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 171 | G → C | 0.002294 | SNP | Missense Mutation | OV |
| 265 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |
| 436 | R → C | 0.002288 | SNP | Missense Mutation | STAD |
| 463 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |
| 509 | R → C | 0.002427 | SNP | Missense Mutation | BLCA |
| 509 | R → C | 0.005435 | SNP | Missense Mutation | ESCA |
| 530 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |