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UniProt ID Gene Symbol Protein Name Organism Length Action
H0Y6Y6 CD1C CD1c molecule Homo sapiens (Human) 281 aa

Protein Details: H0Y6Y6 (CD1C)

Protein Information
AccessionH0Y6Y6
Protein NamesCD1c molecule
Gene SymbolCD1C
OrganismHomo sapiens (Human)
Length281 aa
IsoformsNo isoforms
Related PMIDs 32651440
Database SourcesNo database sources
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501XFLHNWSKGN11FSNEELSDLE21LLFRFYLFGL31TREIQDHASQ41DYSKYPFEVQ
51-10051VKAGCELHSG61KSPEGFFQVA71FNGLDLLSFQ81NTTWVPSPGC91GSLAQSVCHL
101-150101LNHQYEGVTE111TVYNLIRSTC121PRFLLGLLDA131GKMYVHRQVR141PEAWLSSRPS
151-200151LGSGQLLLVC161HASGFYPKPV171WVTWMRNEQE181QLGTKHGDIL191PNADGTWYLQ
201-250201VILEVASEEP211AGLSCRVRHS221SLGGQDIILY231WAHIRTSCET241LPPDSPIVLR
251-281251TQQPRSLVQY261SDAIPSTLHL271NCFSFCIINI281C
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
55 - - -
Deep-Palm: 0.65
90 - - -
Deep-Palm: 0.30
98 - - -
Deep-Palm: 0.41
120 - - -
Deep-Palm: 0.96
160 - - -
Deep-Palm: 0.85
215 - - -
Deep-Palm: 0.97
238 - - -
Deep-Palm: 0.65
272 - - -
Deep-Palm: 0.01
276 - - -
Deep-Palm: 0.01
281 - - -
Deep-Palm: 0.01
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
1
Jurkat T cell
Specificity: 1.000
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
40 S → C 0.002033 SNP Missense Mutation LUSC
89 R → C 0.019272 SNP Missense Mutation SKCM
89 R → C 0.004219 SNP Missense Mutation SARC
154 G → C 0.001764 SNP Missense Mutation LUAD
209 W → C 0.002033 SNP Missense Mutation LUSC
252 G → C 0.002294 SNP Missense Mutation OV
280 C → F 0.001764 SNP Missense Mutation LUAD