Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| H0Y7C1 | ATP1A2 | Sodium/potassium-transporting ATPase subunit alpha | Homo sapiens (Human) | 714 aa |
Protein Details: H0Y7C1 (ATP1A2)
Protein Information
| Accession | H0Y7C1 |
|---|---|
| Protein Names | Sodium/potassium-transporting ATPase subunit alpha |
| Gene Symbol | ATP1A2 |
| Organism | Homo sapiens (Human) |
| Length | 714 aa |
| Isoforms | No isoforms |
| Related PMIDs | 21076176 29575903 31251020 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.923
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
36
LNCaP cells
Specificity: 0.923
36/46 (78.3%)
2
Jurkat T cells
Specificity: 0.051
2/25 (8.0%)
1
HeLa cells
Specificity: 0.026
1/1 (100.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501XQLITGVAVF11LGVSFFVLSL21ILGYSWLEAV31IFLIGIIVAN41VPEGLLATVT
51-10051VCLTLTAKRM61ARKNCLVKNL71EAVETLGSTS81TICSDKTGTL91TQNRMTVAHM
101-150101WFDNQIHEAD111TTEDQSGATF121DKRSPTWTAL131SRIAGLCNRA141VFKAGQENIS
151-200151VSKRDTAGDA161SESALLKCIE171LSCGSVRKMR181DRNPKVAEIP191FNSTNKYQLS
201-250201IHEREDSPQS211HVLVMKGAPE221RILDRCSTIL231VQGKEIPLDK241EMQDAFQNAY
251-300251MELGGLGERV261LGFCQLNLPS271GKFPRGFKFD281TDELNFPTEK291LCFVGLMSMI
301-350301DPPRAAVPDA311VGKCRSAGIK321VIMVTGDHPI331TAKAIAKGVG341IISEGNETVE
351-400351DIAARLNIPM361SQVNPREAKA371CVVHGSDLKD381MTSEQLDEIL391KNHTEIVFAR
401-450401TSPQQKLIIV411EGCQRQGAIV421AVTGDGVNDS431PALKKADIGI441AMGISGSDVS
451-500451KQAADMILLD461DNFASIVTGV471EEGRLIFDNL481KKSIAYTLTS491NIPEITPFLL
501-550501FIIANIPLPL511GTVTILCIDL521GTDMVPAISL531AYEAAESDIM541KRQPRNSQTD
551-600551KLVNERLISM561AYGQIENGFL571PSRLLGIRLD581WDDRTMNDLE591DSYGQEWTYE
601-650601QRKVVEFTCH611TAFFASIVVV621QWADLIICKT631RRNSVFQQGM641KNKILIFGLL
651-700651EETALAAFLS661YCPGMGVALR671MYPLKVTWWF681CAFPYSLLIF691IYDEVRKLIL
701-714701RRYPGGWVEK711ETYY
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 52 | Prediction (Medium) | - | - |
| 65 | Prediction (High) | - | - |
| 83 | Prediction (Low) | - | - |
| 137 | Prediction (Medium) | - | - |
| 168 | Prediction (Low) | - | - |
| 173 | Prediction (High) | - | - |
| 226 | Prediction (Medium) | - | - |
| 264 | Prediction (Medium) | - | - |
| 314 | Prediction (Medium) | - | - |
| 371 | Prediction (Medium) | - | - |
| 413 | CYSMODDB SWISSPALM DBPTM Prediction (High) | - | - |
| 628 | Prediction (High) | - | - |
| 662 | Prediction (Medium) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 51 | R → C | 0.002288 | SNP | Missense Mutation | STAD |
| 143 | C → G | 0.002506 | SNP | Missense Mutation | COAD |
| 247 | C → C | 0.002033 | SNP | Silent | LUSC |
| 267 | R → C | 0.002288 | SNP | Missense Mutation | STAD |
| 267 | R → C | 0.001969 | SNP | Missense Mutation | HNSC |
| 428 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 486 | Y → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 510 | R → C | 0.001969 | SNP | Missense Mutation | HNSC |
| 548 | R → C | 0.002976 | SNP | Missense Mutation | KIRC |
| 664 | G → C | 0.001764 | SNP | Missense Mutation | LUAD |
| 861 | G → C | 0.001764 | SNP | Missense Mutation | LUAD |
| 861 | G → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 976 | R → C | 0.001969 | SNP | Missense Mutation | HNSC |