Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| H0Y804 | AKR1C1 | Aldo-keto reductase family 1 member … | Homo sapiens (Human) | 248 aa |
Protein Details: H0Y804 (AKR1C1)
Protein Information
| Accession | H0Y804 |
|---|---|
| Protein Names | Aldo-keto reductase family 1 member C1 |
| Gene Symbol | AKR1C1 |
| Organism | Homo sapiens (Human) |
| Length | 248 aa |
| Isoforms | No isoforms |
| Related PMIDs | No related PMIDs |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501XSKYQCVKLN11DGHFMPVLGF21GTYAPAEVGL31AIRSKIADGS41VKREDIFYTS
51-10051KLWCNSHRPE61LVRPALERSL71KNLQLDYVDL81YLIHFPVSVK91PGEEVIPKDE
101-150101NGKILFDTVD111LCATWEAVEK121CKDAGLAKSI131GVSNFNRRQL141EMILNKPGLK
151-200151YKPVCNQVEC161HPYFNQRKLL171DFCKSKDIVL181VAYSALGSHR191EEPWVDPNSP
201-248201VLLEDPVLCA211LAKKHKRTPA221LIALRYQLQR231GVVVLAKSYN241EQRIRQNV
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 6 | - | - | - |
GPS-Palm: 0.85
Deep-Palm: 0.02
|
|
| 54 | - | - | - |
Deep-Palm: 0.94
|
|
| 112 | - | - | - |
GPS-Palm: 0.79
Deep-Palm: 0.97
|
|
| 121 | - | - | - |
Deep-Palm: 0.85
|
|
| 155 | - | - | - |
Deep-Palm: 0.46
|
|
| 160 | - | - | - |
Deep-Palm: 0.35
|
|
| 173 | SWISSPALM DBPTM CYSMODDB | Aldo/keto reductase family | - | - |
GPS-Palm: 0.73
Deep-Palm: 0.89
|
| 209 | - | - | - |
GPS-Palm: 0.89
Deep-Palm: 0.98
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 55 | Y → C | 0.002506 | SNP | Missense Mutation | COAD |
| 188 | C → G | 0.002294 | SNP | Missense Mutation | OV |
| 188 | C → R | 0.002545 | SNP | Missense Mutation | GBM |
| 216 | Y → C | 0.001764 | SNP | Missense Mutation | LUAD |
| 263 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 276 | R → C | 0.002506 | SNP | Missense Mutation | COAD |