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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
H0Y950 CD38 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 … Homo sapiens (Human) 151 aa

Protein Details: H0Y950 (CD38)

Protein Information
AccessionH0Y950
Protein NamesADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 (EC 2.4.99.20) (EC 3.2.2.6) (2'-phospho-ADP-ribosyl cyclase) (2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase) (2'-phospho-cyclic-ADP-ribose transferase) (ADP-ribosyl cyclase 1) (Cyclic ADP-ribose hydrolase 1)
Gene SymbolCD38
OrganismHomo sapiens (Human)
Length151 aa
IsoformsNo isoforms
Related PMIDs 19137006 32651440 36430497
Database SourcesNo database sources
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501QPLMKLGTQT11VPCNKILLWS21RIKDLAHQFT31QVQRDMFTLE41DTLLGYLADD
51-10051LTWCEINYQS61CPDWRKDCSN71NPVSVFWKTV81SRRFAEAACD91VVHVMLNGSR
101-150101SKIFDKNSTF111GSVEVHNLQP121EKVQTLEAWV131IHGGREDSRD141LCQDPTIKEL
151-151151E
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
13 N-(deoxy)ribosyltransferase-like ADP-ribosyl cyclase (CD38/157) -
cerebral cortex (36430497)
GPS-Palm: 0.88
Deep-Palm: 0.28
54 - - -
Deep-Palm: 0.17
61 - -
cerebral cortex (36430497)
Deep-Palm: 0.06
68 - -
cerebral cortex (36430497)
Deep-Palm: 0.05
89 - - -
GPS-Palm: 0.72
Deep-Palm: 0.77
142 - - -
Deep-Palm: 0.09
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.571
4
cerebral cortex
Specificity: 0.571
4/4 (100.0%)
3
Jurkat T cell
Specificity: 0.429
3/3 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
47 R → C 0.002506 SNP Missense Mutation COAD
106 Y → C 0.002976 SNP Missense Mutation KIRC
119 C → S 0.002294 SNP Missense Mutation OV