Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| H0Y9V7 | ATP2C1 | Calcium-transporting ATPase type 2C member … | Homo sapiens (Human) | 903 aa |
Protein Details: H0Y9V7 (ATP2C1)
Protein Information
| Accession | H0Y9V7 |
|---|---|
| Protein Names | Calcium-transporting ATPase type 2C member 1 (EC 7.2.2.10) (ATP-dependent Ca(2+) pump PMR1) (Ca(2+)/Mn(2+)-ATPase 2C1) (Secretory pathway Ca(2+)-transporting ATPase type 1) |
| Gene Symbol | ATP2C1 |
| Organism | Homo sapiens (Human) |
| Length | 903 aa |
| Isoforms | No isoforms |
| Related PMIDs | 29575903 31251020 31382980 32944167 36430497 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.844
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
38
LNCaP cells
Specificity: 0.844
38/46 (82.6%)
3
PC3 cells
Specificity: 0.067
3/4 (75.0%)
2
Cerebral cortex
Specificity: 0.044
2/4 (50.0%)
1
U937 cells
Specificity: 0.022
1/1 (100.0%)
1
HeLa cells
Specificity: 0.022
1/1 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501XKCEVSHRRA11FHGWNEFDIS21EDEPLWKKYI31SQFKNPLIML41LLASAVISVL
51-10051MHQFDDAVSI61TVAILIVVTV71AFVQEYRSEK81SLEELSKLVP91PECHCVREGK
101-150101LEHTLARDLV111PGDTVCLSVG121DRVPADLRLF131EAVDLSIDES141SLTGETTPCS
151-200151KVTAPQPAAT161NGDLASRSNI171AFMGTLVRCG181KAKGVVIGTG191ENSEFGEVFK
201-250201MMQAEEAPKT211PLQKSMDLLG221KQLSFYSFGI231IGIIMLVGWL241LGKDILEMFT
251-300251ISVSLAVAAI261PEGLPIVVTV271TLALGVMRMV281KKRAIVKKLP291IVETLGCCNV
301-350301ICSDKTGTLT311KNEMTVTHIF321TSDGLHAEVT331GVGYNQFGEV341IVDGDVVHGF
351-400351YNPAVSRIVE361AGCVCNDAVI371RNNTLMGKPT381EGALIALAMK391MGLDGLQQDY
401-450401IRKAEYPFSS411EQKWMAVKCV421HRTQQDRPEI431CFMKGAYEQV441IKYCTTYQSK
451-500451GQTLTLTQQQ461RDVYQQEKAR471MGSAGLRVLA481LASGPELGQL491TFLGLVGIID
501-550501PPRTGVKEAV511TTLIASGVSI521KMITGDSQET531AVAIASRLGL541YSKTSQSVSG
551-600551EEIDAMDVQQ561LSQIVPKVAV571FYRASPRHKM581KIIKSLQKNG591SVVAMTGDGV
601-650601NDAVALKAAD611IGVAMGQTGT621DVCKEAADMI631LVDDDFQTIM641SAIEEGKGIY
651-700651NNIKNFVRFQ661LSTSIAALTL671ISLATLMNFP681NPLNAMQILW691INIIMDGPPA
701-750701QSLGVEPVDK711DVIRKPPRNW721KDSILTKNLI731LKILVSSIII741VCGTLFVFWR
751-800751ELRDNVITPR761DTTMTFTCFV771FFDMFNALSS781RSQTKSVFEI791GLCSNRMFCY
801-850801AVLGSIMGQL811LVIYFPPLQK821VFQTESLSIL831DLLFLLGLTS841SVCIVAEIIK
851-900851KVERSREKIQ861KHVSSTSSSF871LEVWLWERSG881QQLVEIHPHL891ETGLPLTEDV
901-903901SCV
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 3 | Prediction (High) | - | - |
| 93 | Prediction (Medium) | - | - |
| 95 | Prediction (High) | - | - |
| 116 | Prediction (Medium) | - | - |
| 179 | Prediction (Medium) | - | - |
| 297 | Prediction (High) | - | - |
| 298 | Prediction (High) | - | - |
| 302 | Prediction (Medium) | - | - |
| 363 | Prediction (Medium) | - | - |
| 365 | Prediction (Medium) | - | - |
| 444 | Prediction (Low) | - | - |
| 742 | Prediction (Medium) | - | - |
| 793 | CYSMODDB SWISSPALM DBPTM Prediction (Medium) | Cation transporting ATPase C-terminus | - |
| 799 | Prediction (Medium) | - | - |
| 843 | Prediction (High) | - | - |
| 902 | Prediction (High) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 143 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 195 | C → Vfs*4 | 0.001014 | DEL | Frame Shift Del | BRCA |
| 409 | C → C | 0.002506 | SNP | Silent | COAD |
| 490 | C → Y | 0.001969 | SNP | Missense Mutation | HNSC |
| 760 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 814 | C → C | 0.002288 | SNP | Silent | STAD |
| 972 | C → F | 0.001764 | SNP | Missense Mutation | LUAD |