Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| H0YB86 | PABPC1 | Poly(A) binding protein cytoplasmic 1 | Homo sapiens (Human) | 165 aa |
Protein Details: H0YB86 (PABPC1)
Protein Information
| Accession | H0YB86 |
|---|---|
| Protein Names | Poly(A) binding protein cytoplasmic 1 |
| Gene Symbol | PABPC1 |
| Organism | Homo sapiens (Human) |
| Length | 165 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 32944167 |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501XRKEFSPFGT11ITSAKVMMEG21GRSKGFGFVC31FSSPEEATKA41VTEMNGRIVA
51-10051TKPLYVALAQ61RKEERQAHLT71NQYMQRMASV81RAVPNPVINP91YQPAPPSGYF
101-150101MAAIPQTQNR111AAYYPPSQIA121QLRPSPRWTA131QGARPHPCCS141CTRSGTFDCF
151-165151HVGICPSSRA161KANVG
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 30 | SWISSPALM DBPTM CYSMODDB | Nucleotide-binding alpha-beta plait domain superfamily RNA recognition motif RNA-binding domain superfamily SRA stem-loop-interacting RNA-binding protein/Glycine-rich RNA-binding-like RNA recognition motif domain | - | - |
GPS-Palm: 0.80
Deep-Palm: 0.90
|
| 138 | - | - | - |
Deep-Palm: 0.12
|
|
| 139 | - | - | - |
Deep-Palm: 0.12
|
|
| 141 | - | - | - |
Deep-Palm: 0.09
|
|
| 149 | - | - | - |
Deep-Palm: 0.13
|
|
| 155 | - | - | - |
Deep-Palm: 0.05
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.571
4
PC3
Specificity: 0.571
4/4 (100.0%)
3
LNCaP
Specificity: 0.429
3/3 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 43 | C → C | 0.002288 | SNP | Silent | STAD |
| 67 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 83 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 206 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 309 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 455 | R → C | 0.001014 | SNP | Missense Mutation | BRCA |
| 518 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |
| 518 | R → C | 0.003774 | SNP | Missense Mutation | UCEC |
| 604 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |