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UniProt ID Gene Symbol Protein Name Organism Length Action
H0YB86 PABPC1 Poly(A) binding protein cytoplasmic 1 Homo sapiens (Human) 165 aa

Protein Details: H0YB86 (PABPC1)

Protein Information
Accession H0YB86
Protein Names Poly(A) binding protein cytoplasmic 1
Gene Symbol PABPC1
Organism Homo sapiens (Human)
Length 165 aa
Isoforms No isoforms
Related PMIDs 31251020 32944167
Database Sources CysModDB dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.897
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
35
LNCaP cells
Specificity: 0.897
35/46 (76.1%)
4
PC3 cells
Specificity: 0.103
4/4 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501XRKEFSPFGT11ITSAKVMMEG21GRSKGFGFVC31FSSPEEATKA41VTEMNGRIVA
51-10051TKPLYVALAQ61RKEERQAHLT71NQYMQRMASV81RAVPNPVINP91YQPAPPSGYF
101-150101MAAIPQTQNR111AAYYPPSQIA121QLRPSPRWTA131QGARPHPCCS141CTRSGTFDCF
151-165151HVGICPSSRA161KANVG
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
30 CYSMODDB SWISSPALM DBPTM Prediction (Medium) RNA recognition motif -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
43 C → C 0.002288 SNP Silent STAD
67 R → C 0.001887 SNP Missense Mutation UCEC
83 R → C 0.002506 SNP Missense Mutation COAD
206 R → C 0.001887 SNP Missense Mutation UCEC
309 R → C 0.001887 SNP Missense Mutation UCEC
455 R → C 0.001014 SNP Missense Mutation BRCA
518 R → C 0.002141 SNP Missense Mutation SKCM
518 R → C 0.003774 SNP Missense Mutation UCEC
604 R → C 0.002141 SNP Missense Mutation SKCM