Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| H0YBC1 | LEPROTL1 | Leptin receptor overlapping transcript-like 1 | Homo sapiens (Human) | 136 aa |
Protein Details: H0YBC1 (LEPROTL1)
Protein Information
| Accession | H0YBC1 |
|---|---|
| Protein Names | Leptin receptor overlapping transcript-like 1 |
| Gene Symbol | LEPROTL1 |
| Organism | Homo sapiens (Human) |
| Length | 136 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 31251020 (mass) 32651440 (mass) 36430497 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501XLMLGCALPI11YNKYWPLFVL21FFYILSPIPY31CIARRLVDDT41DAMSNACKEL
51-10051AIFLTTGIVV61SAFGLPIVFA71RAHLMESCSV81AQPGVQWRDL91TSLQALPPGF
101-136101TPFSCLSLPS111SWDYRCPPPR121PADIFCVFSG131DEVSPC
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 6 | Vps55/LEPROT | - | - |
GPS-Palm: 0.97
Deep-Palm: 0.02
|
|
| 31 | Vps55/LEPROT | - | - |
GPS-Palm: 0.93
Deep-Palm: 0.71
|
|
| 47 | SWISSPALM DBPTM CYSMODDB | Vacuolar protein sorting 55 Vps55/LEPROT |
HeLa
(29575903)
|
cerebral cortex
(36430497)
|
Deep-Palm: 0.95
|
| 78 | - | - | - |
GPS-Palm: 0.83
Deep-Palm: 0.93
|
|
| 105 | - | - | - |
GPS-Palm: 0.71
Deep-Palm: 0.94
|
|
| 116 | - | - | - |
Deep-Palm: 0.48
|
|
| 126 | - | - | - |
Deep-Palm: 0.02
|
|
| 136 | - | - | - |
GPS-Palm: 0.96
Deep-Palm: 0.03
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
3
LNCaP
Specificity: 0.429
3/3 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.750
3
Cerebral Cortex (Mass)
Specificity: 0.429
3/4 (75.0%)
1
LNCaP cells (Mass)
Specificity: 0.143
1/4 (25.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 163 | C → C | 0.001887 | SNP | Silent | UCEC |