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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
H0YD13 CD44 CD44 antigen (Extracellular matrix receptor … Homo sapiens (Human) 206 aa

Protein Details: H0YD13 (CD44)

Protein Information
Accession H0YD13
Protein Names CD44 antigen (Extracellular matrix receptor III) (GP90 lymphocyte homing/adhesion receptor) (HUTCH-I) (Hermes antigen) (Hyaluronate receptor) (Phagocytic glycoprotein 1) (Phagocytic glycoprotein I)
Gene Symbol CD44
Organism Homo sapiens (Human)
Length 206 aa
Isoforms No isoforms
Related PMIDs 19801377 22496122 29575903 32944167 36430497
Database Sources CysModDB dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.333
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
4
PC3 cells
Specificity: 0.333
4/4 (100.0%)
4
Cerebral cortex
Specificity: 0.333
4/4 (100.0%)
2
DU145 cells
Specificity: 0.167
2/2 (100.0%)
1
HeLa cells
Specificity: 0.083
1/1 (100.0%)
1
Endothelial cells
Specificity: 0.083
1/2 (50.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
LNCaP cells
Specificity: 0.000
0/46 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MDKFWWHAAW11GLCLVPLSLA21QIDLNITCRF31AGVFHVEKNG41RYSISRTEAA
51-10051DLCKAFNSTL61PTMAQMEKAL71SIGFETCRYG81FIEGHVVIPR91IHPNSICGAN
101-150101TTSGPIRTPQ111IPEWLIILAS121LLALALILAV131CIAVNSRRRC141GQKKKLVINS
151-200151GNGAVEDRKP161SGLNGEASKS171QEMVHLVNKE181SSETPDQFMT191ADETRNLQNV
201-206201DMKIGV
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
28 Prediction (Low) - -
53 Prediction (Medium) - -
77 CYSMODDB SWISSPALM DBPTM Prediction (Medium) Extracellular link domain -
97 Prediction (Medium) - -
131 Prediction (High) - -
140 Prediction (Medium) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
28 C → C 0.002288 SNP Silent STAD
29 R → C 0.001969 SNP Missense Mutation LGG
41 R → C 0.001764 SNP Missense Mutation LUAD
199 S → C 0.002427 SNP Missense Mutation BLCA
245 F → C 0.005618 SNP Missense Mutation PAAD
359 W → C 0.002288 SNP Missense Mutation STAD
542 G → C 0.002545 SNP Missense Mutation GBM