Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| H0YDG7 | PPP2R1B | Protein phosphatase 2 scaffold subunit … | Homo sapiens (Human) | 224 aa |
Protein Details: H0YDG7 (PPP2R1B)
Protein Information
| Accession | H0YDG7 |
|---|---|
| Protein Names | Protein phosphatase 2 scaffold subunit Abeta |
| Gene Symbol | PPP2R1B |
| Organism | Homo sapiens (Human) |
| Length | 224 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 36430497 |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MNLLKDCEAE11VRAAAAHKVK21ELGENLPIED31RETIIMNQIL41PYIKELVSDT
51-10051NQHVKSALAS61VIMGLSTILG71KENTIEHLLP81LFLAQLKDEC91PDVRLNIISN
101-150101LDCVNEVIGI111RQLSQSLLPA121IVELAEDAKW131RVRLAIIEYM141PLLAGQLALS
151-200151EACGQEITTK161QMLPIVLKMA171GDQVANVRFN181VAKSLQKIGP191ILDTNALQGE
201-224201VKPVLQKLGQ211DEDMDVKYFA221QEAI
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 7 | HEAT, type 2 | - | - |
GPS-Palm: 0.91
Deep-Palm: 0.10
|
|
| 90 | - | - | - |
GPS-Palm: 0.82
Deep-Palm: 0.95
|
|
| 103 | SWISSPALM DBPTM CYSMODDB | - |
HeLa
(29575903)
|
Unknown
(32651440)
cerebral cortex
(36430497)
|
GPS-Palm: 0.90
Deep-Palm: 0.86
|
| 153 | - | - | - |
GPS-Palm: 0.80
Deep-Palm: 0.97
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.667
4
cerebral cortex
Specificity: 0.667
4/4 (100.0%)
2
LNCaP
Specificity: 0.333
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 100 | C → C | 0.003460 | SNP | Silent | CESC |
| 117 | R → C | 0.002288 | SNP | Missense Mutation | STAD |
| 233 | R → C | 0.002033 | SNP | Missense Mutation | LUSC |
| 233 | R → C | 0.005618 | SNP | Missense Mutation | PAAD |
| 272 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |
| 389 | C → W | 0.001887 | SNP | Missense Mutation | UCEC |
| 489 | W → C | 0.002506 | SNP | Missense Mutation | COAD |