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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
H0YDJ6 TMEM63B Transmembrane protein 63B Homo sapiens (Human) 27 aa

Protein Details: H0YDJ6 (TMEM63B)

Protein Information
AccessionH0YDJ6
Protein NamesTransmembrane protein 63B
Gene SymbolTMEM63B
OrganismHomo sapiens (Human)
Length27 aa
IsoformsNo isoforms
Related PMIDs 19801377 31251020 32944167
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-271XSVSSSVDFD11QRDNGFCSWL21TAIFRIK
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
17 SWISSPALM DBPTM CYSMODDB -
HeLa (29575903)
-
GPS-Palm: 0.65
Deep-Palm: 0.04
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.500
3
PC3
Specificity: 0.500
3/3 (100.0%)
2
LNCaP
Specificity: 0.333
2/2 (100.0%)
1
DU145 cell
Specificity: 0.167
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
108 R → C 0.001887 SNP Missense Mutation UCEC
128 W → C 0.001764 SNP Missense Mutation LUAD
231 R → C 0.007299 SNP Missense Mutation READ
303 S → C 0.001764 SNP Missense Mutation LUAD
394 R → C 0.003460 SNP Missense Mutation CESC
431 W → C 0.002427 SNP Missense Mutation BLCA
433 R → C 0.002020 SNP Missense Mutation PRAD
542 R → C 0.001969 SNP Missense Mutation LGG
580 G → C 0.002033 SNP Missense Mutation THCA
587 R → C 0.002747 SNP Missense Mutation LIHC
651 Y → C 0.001887 SNP Missense Mutation UCEC
702 R → C 0.002506 SNP Missense Mutation COAD
735 Y → C 0.001887 SNP Missense Mutation UCEC