Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| H0YEE2 | CD81 | CD81 antigen | Homo sapiens (Human) | 303 aa |
Protein Details: H0YEE2 (CD81)
Protein Information
| Accession | H0YEE2 |
|---|---|
| Protein Names | CD81 antigen |
| Gene Symbol | CD81 |
| Organism | Homo sapiens (Human) |
| Length | 303 aa |
| Isoforms | No isoforms |
| Related PMIDs | 19801377 31251020 36430497 31251020 (mass) 32651440 (mass) 36430497 (mass) |
| Database Sources | SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MSGAVTSHLP11QAGLFCTACL21GRWWESLWPS31ALPWQWGQLG41HLGGARLPQA
51-10051RPWDLSRCLV61VACFSPGMWE71RHQTQDVPLP81APEAPSPDEL91AGGVILGVAL
101-150101WLRHDPQTTN111LLYLELGDKP121APNTFYVGIY131ILIAVGAVMM141FVGFLGCYGA
151-200151IQESQCLLGT161FFTCLVILFA171CEVAAGIWGF181VNKDQIAKDV191KQFYDQALQQ
201-250201AVVDDDANNA211KAVVKTFHET221LDCCGSSTLT231ALTTSVLKNN241LCPSGSNIIS
251-300251NLFKEDCHQK261IDDLFSGKLY271LIGIAAIVVA281VIMIFEMILS291MVLCCGIRNS
301-303301SVY
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 16 | - | - | - |
GPS-Palm: 0.72
Deep-Palm: 0.87
|
|
| 19 | - | - | - |
GPS-Palm: 0.86
Deep-Palm: 0.92
|
|
| 58 | - | - | - |
Deep-Palm: 0.93
|
|
| 63 | - | - | - |
GPS-Palm: 0.86
Deep-Palm: 0.71
|
|
| 147 | - | - | - |
GPS-Palm: 0.76
Deep-Palm: 0.95
|
|
| 156 | - | - | - |
Deep-Palm: 0.89
|
|
| 164 | - | - | - |
Deep-Palm: 0.94
|
|
| 171 | - | - | - |
Deep-Palm: 0.38
|
|
| 223 | - | - |
cerebral cortex
(36430497)
LNCaP
(31251020)
|
GPS-Palm: 0.82
Deep-Palm: 0.95
|
|
| 224 | - | - |
cerebral cortex
(36430497)
LNCaP
(31251020)
|
GPS-Palm: 0.90
Deep-Palm: 0.92
|
|
| 242 | - | - |
cerebral cortex
(36430497)
LNCaP
(31251020)
|
GPS-Palm: 0.75
Deep-Palm: 0.88
|
|
| 257 | - | - |
cerebral cortex
(36430497)
|
GPS-Palm: 0.65
Deep-Palm: 0.36
|
|
| 294 | - | - | - |
GPS-Palm: 0.91
Deep-Palm: 0.03
|
|
| 295 | - | - | - |
GPS-Palm: 0.94
Deep-Palm: 0.03
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.667
4
cerebral cortex
Specificity: 0.333
4/4 (100.0%)
1
LNCaP
Specificity: 0.083
1/1 (100.0%)
1
DU145 cell
Specificity: 0.083
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.667
4
Cerebral Cortex (Mass)
Specificity: 0.333
4/4 (100.0%)
2
LNCaP cells (Mass)
Specificity: 0.167
2/4 (50.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 157 | C → F | 0.003559 | SNP | Missense Mutation | KIRP |
| ? | ? → ? | 0.001887 | SNP | Missense Mutation | UCEC |