Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| H0YEF4 | ZDHHC5 | protein S-acyltransferase (EC 2.3.1.225) | Homo sapiens (Human) | 300 aa |
Protein Details: H0YEF4 (ZDHHC5)
Protein Information
| Accession | H0YEF4 |
|---|---|
| Protein Names | protein S-acyltransferase (EC 2.3.1.225) |
| Gene Symbol | ZDHHC5 |
| Organism | Homo sapiens (Human) |
| Length | 300 aa |
| Isoforms | No isoforms |
| Related PMIDs | 19801377 29575903 31251020 32944167 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.851
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
40
LNCaP cells
Specificity: 0.851
40/46 (87.0%)
4
PC3 cells
Specificity: 0.085
4/4 (100.0%)
2
DU145 cells
Specificity: 0.043
2/2 (100.0%)
1
HeLa cells
Specificity: 0.021
1/1 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501RAEEDEDKED11DFRAPLYKTV21EIKGIQVRMK31WCATCRFYRP41PRCSHCSVCD
51-10051NCVEVTGKFR61GGVNPFTNGC71CNNVSRVLCS81SPAPRYLGRP91KKEKTIVIRP
101-150101PFLRPEVSDG111QITVKIMDNG121IQGELRRTKS131KGSLEITESQ141SADAEPPPPP
151-200151KPDLSRYTGL161RTHLGLATNE171DSSLLAKDSP181PTPTMYKYRP191GYSSSSTSAA
201-250201MPHSSSAKLS211RGDSLKEPTS221IAESSRHPSY231RSEPSLEPES241FRSPTFGKSF
251-300251HFDPLSSGSR261SSSLKSAQGT271GFELGQLQSI281RSEGTTSTSY291KSLANQTRNG
Palmitoylation Sites Details
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 102 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 102 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 134 | C → C | 0.001014 | SNP | Silent | BRCA |
| 140 | C → C | 0.006993 | SNP | Silent | LAML |
| 215 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 409 | S → C | 0.001014 | SNP | Missense Mutation | BRCA |
| 538 | R → C | 0.002288 | SNP | Missense Mutation | STAD |
| 538 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 538 | R → C | 0.003774 | SNP | Missense Mutation | UCEC |
| 708 | G → C | 0.001014 | SNP | Missense Mutation | BRCA |
| 236* | C → ? | 0.001887 | SNP | Nonsense Mutation | UCEC |