Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| H0YEL7 | ACAT1 | Acetyl-CoA acetyltransferase 1 | Homo sapiens (Human) | 136 aa |
Protein Details: H0YEL7 (ACAT1)
Protein Information
| Accession | H0YEL7 |
|---|---|
| Protein Names | Acetyl-CoA acetyltransferase 1 |
| Gene Symbol | ACAT1 |
| Organism | Homo sapiens (Human) |
| Length | 136 aa |
| Isoforms | No isoforms |
| Related PMIDs | 29575903 31251020 32944167 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.915
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
43
LNCaP cells
Specificity: 0.915
43/46 (93.5%)
3
PC3 cells
Specificity: 0.064
3/4 (75.0%)
1
HeLa cells
Specificity: 0.021
1/1 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501XKLGSIAIQG11AIEKAGIPKE21EVKEAYMGNV31LQGGEGQAPT41RQAVLGAGLP
51-10051ISTPCTTINK61VCASGMKAIM71MASQSLMCGH81QDVMVAGGME91SMSNVPYVMN
101-136101RGSTPYGGVK111LEDLIVKDGL121TDVYNKIHMV131NVIFSG
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 55 | Prediction (Medium) | - | - |
| 62 | Prediction (Medium) | - | - |
| 78 | Prediction (Low) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 55 | F → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 357 | S → C | 0.003460 | SNP | Missense Mutation | CESC |
| 407 | Y → C | 0.002506 | SNP | Missense Mutation | COAD |