Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| H0YGV7 | MAN1B1 | alpha-1,2-Mannosidase (EC 3.2.1.-) | Homo sapiens (Human) | 550 aa |
Protein Details: H0YGV7 (MAN1B1)
Protein Information
| Accession | H0YGV7 |
|---|---|
| Protein Names | alpha-1,2-Mannosidase (EC 3.2.1.-) |
| Gene Symbol | MAN1B1 |
| Organism | Homo sapiens (Human) |
| Length | 550 aa |
| Isoforms | No isoforms |
| Related PMIDs | 29575903 31251020 32944167 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.900
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
36
LNCaP cells
Specificity: 0.900
36/46 (78.3%)
3
PC3 cells
Specificity: 0.075
3/4 (75.0%)
1
HeLa cells
Specificity: 0.025
1/1 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MAACEGRRSG11ALGSSQSDFL21TPPVGGAPWA31VATTVVMYPP41PPPPPHRDFI
51-10051SVTLSFGENY61DNSKSWRRRS71CWRKWKQLSR81LQRNMILFLL91AFLLFCGLLF
101-150101YINLADHWKA111LAFRLEEEQK121MRPEIAGLKP131ANPPVLPAPQ141KADTDPENLP
151-200151EISSQKTQRH161IQRGPPHLQI171RPPSQDLKDG181TQEEATKRQE191APVDPRPEGD
201-250201PQRTVISWRG211AVIEPEQGTE221LPSRRAEVPT231KPPLPPARTQ241GTPVHLNYRQ
251-300251KGVIDVFLHA261WKGYRKFAWG271HDELKPVSRS281FSEWFGLGLT291LIDALDTMWI
301-350301LGLRKEFEEA311RKWVSKKLHF321EKDVDVNLFE331STIRILGGLL341SAYHLSGDSL
351-400351FLRKAEDFGN361RLMPAFRTPS371KIPYSDVNIG381TGVAHPPRWT391SDSTVAEVTS
401-450401IQLEFRELSR411LTGDKKFQEA421VEKVTQHIHG431LSGKKDGLVP441MFINTHSGLF
451-500451THLGVFTLGA461RADSYYEYLL471KQWIQGGKQE481TQLLEDYVEA491IEGVRTHLLR
501-550501HSEPSKLTFV511GELAHGRFSA521KMGRWLWAST531TACPPATWSW541PRSSWRLVTR
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 4 | Prediction (High) | - | - |
| 71 | Prediction (Medium) | - | - |
| 533 | Prediction (Medium) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 249 | R → C | 0.002288 | SNP | Missense Mutation | STAD |
| 265 | R → C | 0.003460 | SNP | Missense Mutation | CESC |
| 281 | F → C | 0.002545 | SNP | Missense Mutation | GBM |
| 502 | S → C | 0.001969 | SNP | Missense Mutation | HNSC |
| 619 | W → C | 0.001014 | SNP | Missense Mutation | BRCA |