Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
H0YGW7 ABCF1 ATP-binding cassette sub-family F member … Homo sapiens (Human) 596 aa

Protein Details: H0YGW7 (ABCF1)

Protein Information
AccessionH0YGW7
Protein NamesATP-binding cassette sub-family F member 1 (ATP-binding cassette 50)
Gene SymbolABCF1
OrganismHomo sapiens (Human)
Length596 aa
IsoformsNo isoforms
Related PMIDs 31251020 31382980
Database SourcesNo database sources
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501XAHLSKKEKK11KLKKQMEYER21QVASLKAANA31AENDFSVSQA41EMSSRQAMLE
51-10051NASDIKLEKF61SISAHGKELF71VNADLYIVAG81RRYGLVGPNG91KGKTTLLKHI
101-150101ANRALSIPPN111IDVLLCEQEV121VADETPAVQA131VLRADTKRLK141LLEEERRLQG
151-200151QLEQGDDTAA161ERLEKVYEEL171RATGAAAAEA181KARRILAGLG191FDPEMQNRPT
201-250201QKFSGGWRMR211VSLARALFME221PTLLMLDEPT231NHLDLNAVIW241LNNYLQGWRK
251-300251TLLIVSHDQG261FLDDVCTDII271HLDAQRLHYY281RGNYMTFKKM291YQQKQKELLK
301-350301QYEKQEKKLK311ELKAGGKSTK321QAEKQTKEAL331TRKQQKCRRK341NQDEESQEAP
351-400351ELLKRPKEYT361VRFTFPDPPP371LSPPVLGLHG381VTFGYQGQKP391LFKNLDFGID
401-450401MDSRICIVGP411NGVGKSTLLL421LLTGKLTPTH431GEMRKNHRLK441IGFFNQQYAE
451-500451QLRMEETPTE461YLQRGFNLPY471QDARKCLGRF481GLESHAHTIQ491ICKLSGGQKA
501-550501RVVFAELACR511EPDVLILDEP521TNNLDIESID531ALGEAINEYK541GAVIVVSHDA
551-596551RLITETNCQL561WVVEEQSVSQ571IDGDFEDYKR581EVLEALGEVM591VSRPRE
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
116 - - -
Deep-Palm: 0.97
266 - - -
Deep-Palm: 0.88
337 - - -
Deep-Palm: 0.89
406 - - -
GPS-Palm: 0.80
Deep-Palm: 0.96
476 - - -
GPS-Palm: 0.72
Deep-Palm: 0.78
492 - - -
GPS-Palm: 0.80
Deep-Palm: 0.96
509 - - -
GPS-Palm: 0.85
Deep-Palm: 0.98
558 - - -
Deep-Palm: 0.94
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.500
1
LNCaP
Specificity: 0.500
1/1 (100.0%)
1
U937 cell
Specificity: 0.500
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
22 S → C 0.002141 SNP Missense Mutation SKCM
294 R → C 0.002288 SNP Missense Mutation STAD
332 Y → C 0.001887 SNP Missense Mutation UCEC
457 R → C 0.004219 SNP Missense Mutation SARC
459 R → C 0.001969 SNP Missense Mutation LGG
604 R → C 0.001887 SNP Missense Mutation UCEC
655 C → F 0.002294 SNP Missense Mutation OV
702 R → C 0.001887 SNP Missense Mutation UCEC
744 S → C 0.001014 SNP Missense Mutation BRCA
788 Y → C 0.001764 SNP Missense Mutation LUAD