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UniProt ID Gene Symbol Protein Name Organism Length Action
H0YHH6 ATP2B1 ATPase plasma membrane Ca2+ transporting … Homo sapiens (Human) 162 aa

Protein Details: H0YHH6 (ATP2B1)

Protein Information
AccessionH0YHH6
Protein NamesATPase plasma membrane Ca2+ transporting 1
Gene SymbolATP2B1
OrganismHomo sapiens (Human)
Length162 aa
IsoformsNo isoforms
Related PMIDs 26876311 31251020 32944167 36430497
Database SourcesNo database sources
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501XFNEINARKI11HGERNVFEGI21FNNAIFCTIV31LGTFVVQLIS41TIPTSRLKFL
51-10051KEAGHGTQKE61EIPEEELAED71VEEIDHAERE81LRRGQILWFR91GLNRIQTQIR
101-150101VVNAFRSSLY111EGLEKPESRS121SIHNFMTHPE131FRIEDSEPHI141PLIDDTDAED
151-162151DAPTKRNSSP161PP
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
27 - - -
Deep-Palm: 0.18
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.333
4
PC3
Specificity: 0.333
4/4 (100.0%)
4
cerebral cortex
Specificity: 0.333
4/4 (100.0%)
3
LNCaP
Specificity: 0.250
3/3 (100.0%)
1
frontal cortex
Specificity: 0.083
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
162 S → C 0.004219 SNP Missense Mutation SARC
164 V → Cfs*7 0.003460 INS Frame Shift Ins CESC
221 G → C 0.002033 SNP Missense Mutation LUSC
320 R → C 0.003774 SNP Missense Mutation UCEC
416 F → C 0.001014 SNP Missense Mutation BRCA
697 C → W 0.003460 SNP Missense Mutation CESC
789 R → C 0.003460 SNP Missense Mutation CESC
875 C → F 0.001764 SNP Missense Mutation LUAD
1102 R → C 0.002288 SNP Missense Mutation STAD
1102 R → C 0.003460 SNP Missense Mutation CESC
1125 R → C 0.002141 SNP Missense Mutation SKCM