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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
H0YKN4 ANXA2 Annexin A2 Homo sapiens (Human) 69 aa

Protein Details: H0YKN4 (ANXA2)

Protein Information
AccessionH0YKN4
Protein NamesAnnexin A2
Gene SymbolANXA2
OrganismHomo sapiens (Human)
Length69 aa
IsoformsNo isoforms
Related PMIDs 31251020 32944167
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MSTVHEILCK11LSLEGDHSTP21PSAYGSVKAY31TNFDAERDAL41NIETAIKTKG
51-6951ARPEPRSYQT61LEKESLVPF
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
9 SWISSPALM DBPTM CYSMODDB Annexin A2
HeLa (29575903)
-
Deep-Palm: 0.04
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.800
4
PC3
Specificity: 0.800
4/4 (100.0%)
1
LNCaP
Specificity: 0.200
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
165 G → C 0.002033 SNP Missense Mutation LUSC
213 W → C 0.005435 SNP Missense Mutation ESCA