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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
H0YL10 CD276 CD276 molecule Homo sapiens (Human) 199 aa

Protein Details: H0YL10 (CD276)

Protein Information
Accession H0YL10
Protein Names CD276 molecule
Gene Symbol CD276
Organism Homo sapiens (Human)
Length 199 aa
Isoforms No isoforms
Related PMIDs 19801377 31251020
Database Sources CysModDB dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.952
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
40
LNCaP cells
Specificity: 0.952
40/46 (87.0%)
2
DU145 cells
Specificity: 0.048
2/2 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MRVRVADEGS11FTCFVSIRDF21GSAAVSLQVA31APYSKPSMTL41EPNKDLRPGD
51-10051TVTITCSSYR61GYPEAEVFWQ71DGQGVPLTGN81VTTSQMANEQ91GLFDVHSVLR
101-150101VVLGANGTYS111CLVRNPVLQQ121DAHGSVTITE131ALWVTVGLSV141CLIALLVALA
151-199151FVCWRKIKQS161CEEENAGAED171QDGEGEGSKT181ALQPLKHSDS191KEDDGQEIA
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
13 Prediction (Low) - -
56 CYSMODDB SWISSPALM DBPTM Prediction (Medium) Immunoglobulin domain -
111 Prediction (Medium) - -
141 Prediction (Low) - -
153 Prediction (High) - -
161 CYSMODDB SWISSPALM DBPTM - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
24 C → C 0.002427 SNP Silent BLCA
92 R → C 0.002506 SNP Missense Mutation COAD
92 R → C 0.003460 SNP Missense Mutation CESC
130 G → C 0.010870 SNP Missense Mutation ACC
349 S → C 0.001764 SNP Missense Mutation LUAD
? ? → ? 0.002288 SNP Missense Mutation STAD