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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
H3BLU7 AKR7A2 Aldo-keto reductase family 7 member … Homo sapiens (Human) 324 aa

Protein Details: H3BLU7 (AKR7A2)

Protein Information
AccessionH3BLU7
Protein NamesAldo-keto reductase family 7 member A2
Gene SymbolAKR7A2
OrganismHomo sapiens (Human)
Length324 aa
IsoformsNo isoforms
Related PMIDs 31251020 31382980
Database SourcesSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MLSAASRVVS11RAAVHCALRS21PPPEARALAM31SRPPPPRVAS41VLGTMEMGRR
51-10051MDAPASAAAV61RAFLERGHTE71LDTAFMYSDG81QSETILGGLG91LGLGGGDCRV
101-150101KIATKANPWD111GKSLKPDSVR121SQLETSLKRL131QCPQVDLFYL141HAPDHGTPVE
151-200151ETLHACQRLH161QEGMYNATTR171QVETELFPCL181RHFGLRFYAY191NPLAGGLLTG
201-250201KYKYEDKDGK211QPVGRFFGNS221WAETYRNRFW231KEHHFEAIAL241VEKALQAAYG
251-300251ASAPSVTSAA261LRWMYHHSQL271QGAHGDAVIL281GMSSLEQLEQ291NLAATEEGPL
301-324301EPAVVDAFNQ311AWHLVAHECP321NYFR
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
6 - - -
GPS-Palm: 0.93
16 - - -
Deep-Palm: 0.98
88 - - -
GPS-Palm: 0.94
98 - - -
Deep-Palm: 0.98
132 - - -
Deep-Palm: 0.95
156 - - -
Deep-Palm: 0.30
169 - - -
GPS-Palm: 0.91
179 - -
Unknown (32651440)
Deep-Palm: 0.85
319 - - -
Deep-Palm: 0.02
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.750
3
LNCaP
Specificity: 0.750
3/3 (100.0%)
1
U937 cell
Specificity: 0.250
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
225 Y → C 0.002288 SNP Missense Mutation STAD
237 Y → C 0.002288 SNP Missense Mutation STAD