Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| H3BM38 | SNAP23 | Synaptosomal-associated protein | Homo sapiens (Human) | 125 aa |
Protein Details: H3BM38 (SNAP23)
Protein Information
| Accession | H3BM38 |
|---|---|
| Protein Names | Synaptosomal-associated protein |
| Gene Symbol | SNAP23 |
| Organism | Homo sapiens (Human) |
| Length | 125 aa |
| Isoforms | No isoforms |
| Related PMIDs | 19801377 21076176 22496122 29575903 31251020 32651440 32944167 36430497 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.702
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
40
LNCaP cells
Specificity: 0.702
40/46 (87.0%)
5
Jurkat T cells
Specificity: 0.088
5/25 (20.0%)
4
PC3 cells
Specificity: 0.070
4/4 (100.0%)
4
Cerebral cortex
Specificity: 0.070
4/4 (100.0%)
2
DU145 cells
Specificity: 0.035
2/2 (100.0%)
1
HeLa cells
Specificity: 0.018
1/1 (100.0%)
1
Endothelial cells
Specificity: 0.018
1/2 (50.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MDNLSSEEIQ11QRAHQITDES21LESTRRILGL31AIESQDAGIK41TITMLDEQKE
51-10051QLNRIEEGLD61QINKDMRETE71KTLTELNKCC81GLCVCPCNRT91KNFESGKAYK
101-125101TTWGDGGENS111PCNVVSKQPG121PVTNG
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 79 | Experimental CYSMODDB SWISSPALM DBPTM Prediction (Medium) | SNAP-25 family | 19801377 |
| 80 | Experimental CYSMODDB SWISSPALM DBPTM Prediction (High) | SNAP-25 family | 19801377 |
| 83 | Experimental CYSMODDB SWISSPALM DBPTM Prediction (High) | SNAP-25 family | 19801377 |
| 85 | Experimental CYSMODDB SWISSPALM DBPTM Prediction (High) | SNAP-25 family | 19801377 |
| 87 | Experimental CYSMODDB SWISSPALM DBPTM Prediction (High) | SNAP-25 family | 19801377 |
| 112 | Experimental | SNAP-25 family | 19801377 |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 48 | Q → Cfs*22 | 0.001887 | INS | Frame Shift Ins | UCEC |
| 142 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |