Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| H3BM89 | RPL4; hCG_2004318 | Large ribosomal subunit protein uL4 … | Homo sapiens (Human) | 333 aa |
Protein Details: H3BM89 (RPL4)
Protein Information
| Accession | H3BM89 |
|---|---|
| Protein Names | Large ribosomal subunit protein uL4 (60S ribosomal protein L4) |
| Gene Symbol | RPL4; hCG_2004318 |
| Organism | Homo sapiens (Human) |
| Length | 333 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 32944167 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.927
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
38
LNCaP cells
Specificity: 0.927
38/46 (82.6%)
3
PC3 cells
Specificity: 0.073
3/4 (75.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MCRGGRMFAP11TKTWRRWHRR21VNTTQKRYAI31CSALAASALP41ALVMSKGHRI
51-10051EEVPELPLVV61EDKVEGYKKT71KEAVLLLKKL81KAWNDIKKVY91ASQRMRAGKG
101-150101KMRNRRRIQR111RGPCIIYNED121NGIIKAFRNI131PGITLLNVSK141LNILKLAPGG
151-200151HVGRFCIWTE161SAFRKLDELY171GTWRKAASLK181SNYNLPMHKM191INTDLSRILK
201-250201SPEIQRALRA211PRKKIHRRVL221KKNPLKNLRI231MLKLNPYAKT241MRRNTILRQA
251-300251RNHKLRVDKA261AAAAAALQAK271SDEKAAVAGK281KPVVGKKGKK291AAVGVKKQKK
301-333301PLVGKKAAAT311KKPAPEKKPA321EKKPTTEEKK331PAA
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 2 | Prediction (High) | - | - |
| 31 | Prediction (Medium) | - | - |
| 114 | Prediction (Medium) | - | - |
| 156 | CYSMODDB SWISSPALM DBPTM Prediction (High) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 97 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 143 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |
| 200 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 268 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 336 | R → C | 0.002033 | SNP | Missense Mutation | THCA |
| 342 | R → C | 0.001764 | SNP | Missense Mutation | LUAD |