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UniProt ID Gene Symbol Protein Name Organism Length Action
H3BMN2 SCAMP2 Secretory carrier-associated membrane protein (Secretory … Homo sapiens (Human) 93 aa

Protein Details: H3BMN2 (SCAMP2)

Protein Information
AccessionH3BMN2
Protein NamesSecretory carrier-associated membrane protein (Secretory carrier membrane protein)
Gene SymbolSCAMP2
OrganismHomo sapiens (Human)
Length93 aa
IsoformsNo isoforms
Related PMIDs 19801377
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MLYYLWMLHS11VTLFLNLLAC21LAWFSGNSSK31GVDFGLSILW41FLIFTPCAFL
51-9351CWYRPIYKAF61RSDNSFSFFV71FFFVFFCQIG81IYIIQLVGIP91GLG
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
20 SCAMP - -
Deep-Palm: 0.67
47 SWISSPALM DBPTM CYSMODDB SCAMP family SCAMP - -
GPS-Palm: 0.75
Deep-Palm: 0.66
51 SCAMP - -
GPS-Palm: 0.86
Deep-Palm: 0.39
77 - - -
Deep-Palm: 0.05
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
1
DU145 cell
Specificity: 1.000
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
207 Y → C 0.002747 SNP Missense Mutation LIHC
215 S → C 0.002033 SNP Missense Mutation LUSC
227 C → Lfs*30 0.002288 INS Frame Shift Ins STAD
227 C → Vfs*3 0.003774 DEL Frame Shift Del UCEC
227 C → Lfs*30 0.001887 INS Frame Shift Ins UCEC