Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| H3BPL9 | SCAMP2 | Secretory carrier-associated membrane protein (Secretory … | Homo sapiens (Human) | 278 aa |
Protein Details: H3BPL9 (SCAMP2)
Protein Information
| Accession | H3BPL9 |
|---|---|
| Protein Names | Secretory carrier-associated membrane protein (Secretory carrier membrane protein) |
| Gene Symbol | SCAMP2 |
| Organism | Homo sapiens (Human) |
| Length | 278 aa |
| Isoforms | No isoforms |
| Related PMIDs | 19801377 31251020 32651440 |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501SETNAATTVP11VTQLPGSSQP21AVLQPSVEPT31QPTPQAVVSA41AQAGLLRQQE
51-10051ELDRKAAELE61RKERELQNTV71ANLHVRQNNW81PPLPSWCPVK91PCFYQDFSTE
101-150101IPADYQRICK111MLYYLWMLHS121VTLFLNLLAC131LAWFSGNSSK141GVDFGLSILW
151-200151FLIFTPCAFL161CWYRPIYKAF171RSDNSFSFFV181FFFVFFCQIG191IYIIQLVGIP
201-250201GLGDSGWIAA211LSTLDNHSLA221ISVIMMVVAG231FFTLCAVLSV241FLLQRVSGVG
251-278251RADSKWEEAG261NRFLPLPRDV271FHHCSWAS
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 87 | - | - | - |
GPS-Palm: 0.70
Deep-Palm: 0.40
|
|
| 92 | - | - | - |
GPS-Palm: 0.78
Deep-Palm: 0.65
|
|
| 109 | - | - | - |
Deep-Palm: 0.08
|
|
| 130 | - | - | - |
Deep-Palm: 0.67
|
|
| 157 | SWISSPALM DBPTM CYSMODDB | SCAMP family | - | - |
GPS-Palm: 0.75
Deep-Palm: 0.66
|
| 161 | - | - | - |
GPS-Palm: 0.86
Deep-Palm: 0.39
|
|
| 187 | - | - | - |
Deep-Palm: 0.05
|
|
| 235 | - | - | - |
GPS-Palm: 0.69
Deep-Palm: 0.91
|
|
| 274 | - | - | - |
GPS-Palm: 0.93
Deep-Palm: 0.03
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.667
4
LNCaP
Specificity: 0.667
4/4 (100.0%)
1
Jurkat T cell
Specificity: 0.167
1/1 (100.0%)
1
DU145 cell
Specificity: 0.167
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 207 | Y → C | 0.002747 | SNP | Missense Mutation | LIHC |
| 215 | S → C | 0.002033 | SNP | Missense Mutation | LUSC |
| 227 | C → Lfs*30 | 0.002288 | INS | Frame Shift Ins | STAD |
| 227 | C → Vfs*3 | 0.003774 | DEL | Frame Shift Del | UCEC |
| 227 | C → Lfs*30 | 0.001887 | INS | Frame Shift Ins | UCEC |