Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| H3BR35 | GSPT1 | G1 to S phase transition … | Homo sapiens (Human) | 475 aa |
Protein Details: H3BR35 (GSPT1)
Protein Information
| Accession | H3BR35 |
|---|---|
| Protein Names | G1 to S phase transition 1 |
| Gene Symbol | GSPT1 |
| Organism | Homo sapiens (Human) |
| Length | 475 aa |
| Isoforms | No isoforms |
| Related PMIDs | 32944167 |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501XSNSAVSMEL11SEPIENGETE21MSPEESWEHK31EEISEAEPGG41GSLGDGRPPE
51-10051ESAHEMMEEE61EEIPKPKSVV71APPGAPKKEH81VNVVFIGHVD91AGKSTIGGQI
101-150101MYLTGMVDKR111TLEKYEREAK121EKNRETWYLS131WALDTNQEER141DKGKTVEVGR
151-200151AYFETEKKHF161TILDAPGHKS171FVPNMIGGAS181QADLAVLVIS191ARKGEFETGF
201-250201EKGGQTREHA211MLAKTAGVKH221LIVLINKMDD231PTVNWSNERY241EECKEKLVPF
251-300251LKKVGFNPKK261DIHFMPCSGL271TGANLKEQSD281FCPWYIGLPF291IPYLDNLPNF
301-350301NRSVDGPIRL311PIVDKYKDMG321TVVLGKLESG331SICKGQQLVM341MPNKHNVEVL
351-400351GILSDDVETD361TVAPGENLKI371RLKGIEEEEI381LPGFILCDPN391NLCHSGRTFD
401-450401AQALICLVDK411KSGEKSKTRP421RFVKQDQVCI431ARLRTAGTIC441LETFKDFPQM
451-475451GRFTLRDEGK461TIAIGKVLKL471VPEKD
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 243 | - | - | - |
Deep-Palm: 0.87
|
|
| 267 | - | - | - |
GPS-Palm: 0.81
Deep-Palm: 0.89
|
|
| 282 | - | - | - |
Deep-Palm: 0.88
|
|
| 333 | - | - | - |
GPS-Palm: 0.85
Deep-Palm: 0.96
|
|
| 387 | SWISSPALM DBPTM CYSMODDB | - | - |
Unknown
(32651440)
|
Deep-Palm: 0.87
|
| 393 | SWISSPALM DBPTM CYSMODDB | - | - |
Unknown
(32651440)
|
Deep-Palm: 0.65
|
| 406 | - | - | - |
GPS-Palm: 0.94
Deep-Palm: 0.93
|
|
| 429 | - | - | - |
GPS-Palm: 0.94
Deep-Palm: 0.85
|
|
| 440 | - | - | - |
GPS-Palm: 0.92
Deep-Palm: 0.93
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
3
PC3
Specificity: 1.000
3/3 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 410 | Y → C | 0.002545 | SNP | Missense Mutation | GBM |
| 456 | R → C | 0.001969 | SNP | Missense Mutation | HNSC |