Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
H3BR68 ALDOA fructose-bisphosphate aldolase (EC 4.1.2.13) Homo sapiens (Human) 130 aa

Protein Details: H3BR68 (ALDOA)

Protein Information
AccessionH3BR68
Protein Namesfructose-bisphosphate aldolase (EC 4.1.2.13)
Gene SymbolALDOA
OrganismHomo sapiens (Human)
Length130 aa
IsoformsNo isoforms
Related PMIDs 31251020 32944167 36430497
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501XPGHACTQKF11SHEEIAMATV21TALRRTVPPA31VTGITFLSGG41QSEEEASINL
51-10051NAINKCPLLK61PWALTFSYGR71ALQASALKAW81GGKKENLKAA91QEEYVKRALA
101-130101NSLACQGKYT111PSGQAGAAAS121ESLFVSNHAY
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
6 Aldolase-type TIM barrel Aldolase Fructose-bisphosphate aldolase, class-I - -
GPS-Palm: 0.89
Deep-Palm: 0.02
56 SWISSPALM DBPTM CYSMODDB Fructose-bisphosphate aldolase class-I
HeLa (29575903)
Unknown (32651440)
cerebral cortex (36430497)
GPS-Palm: 0.87
Deep-Palm: 0.95
105 SWISSPALM DBPTM CYSMODDB Fructose-bisphosphate aldolase class-I
HeLa (29575903)
Unknown (32651440)
cerebral cortex (36430497)
GPS-Palm: 0.92
Deep-Palm: 0.96
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.400
4
PC3
Specificity: 0.400
4/4 (100.0%)
4
cerebral cortex
Specificity: 0.400
4/4 (100.0%)
2
LNCaP
Specificity: 0.200
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
76 G → C 0.002506 SNP Missense Mutation COAD
149 R → C 0.002506 SNP Missense Mutation COAD
201 R → C 0.002545 SNP Missense Mutation GBM
201 R → C 0.003774 SNP Missense Mutation UCEC
204 Y → C 0.001887 SNP Missense Mutation UCEC