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Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| H3BR99 | SNAP23 | Synaptosome associated protein 23 | Homo sapiens (Human) | 90 aa |
Protein Details: H3BR99 (SNAP23)
Protein Information
| Accession | H3BR99 |
|---|---|
| Protein Names | Synaptosome associated protein 23 |
| Gene Symbol | SNAP23 |
| Organism | Homo sapiens (Human) |
| Length | 90 aa |
| Isoforms | No isoforms |
| Related PMIDs | 19137006 29575903 31251020 32944167 36430497 |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501XGIKTITMLD11EQKEQLNRIE21EGLDQINKDM31RETEKTLTEL41NKCCGLCVCP
51-9051CNSKQTDLGI61TEDALGKHAE71LKTILFQAKN81FKAWTARYLH
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 43 | SWISSPALM DBPTM CYSMODDB | - | - | - |
GPS-Palm: 0.72
Deep-Palm: 0.54
|
| 44 | SWISSPALM DBPTM CYSMODDB | - | - | - |
GPS-Palm: 0.94
Deep-Palm: 0.58
|
| 47 | - | - | - |
GPS-Palm: 0.93
Deep-Palm: 0.65
|
|
| 49 | - | - | - |
GPS-Palm: 0.91
Deep-Palm: 0.60
|
|
| 51 | - | - | - |
GPS-Palm: 0.92
Deep-Palm: 0.58
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.308
4
PC3
Specificity: 0.308
4/4 (100.0%)
4
cerebral cortex
Specificity: 0.308
4/4 (100.0%)
2
HeLa cell
Specificity: 0.154
2/2 (100.0%)
2
Jurkat T cell
Specificity: 0.154
2/2 (100.0%)
1
LNCaP
Specificity: 0.077
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 48 | Q → Cfs*22 | 0.001887 | INS | Frame Shift Ins | UCEC |
| 142 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |