Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
H3BRF9 ZFYVE19 Abscission/NoCut checkpoint regulator (Zinc finger … Homo sapiens (Human) 448 aa

Protein Details: H3BRF9 (ZFYVE19)

Protein Information
Accession H3BRF9
Protein Names Abscission/NoCut checkpoint regulator (Zinc finger FYVE domain-containing protein 19)
Gene Symbol ZFYVE19
Organism Homo sapiens (Human)
Length 448 aa
Isoforms No isoforms
Related PMIDs 29575903 31251020
Database Sources No database sources
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.833
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
5
LNCaP cells
Specificity: 0.833
5/46 (10.9%)
1
HeLa cells
Specificity: 0.167
1/1 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MPAVAEALGQ11EGPPDLSRSA21FLATVLTSLS31AAFSSMPSSA41YRSIYPAVLG
51-10051ATMESRCYGC61AVKFTLFKKE71YGCKNCGRAF81CSGCLSFSAA91VPRTGNTQQK
101-150101VCKQCHEVLT111RGSSANASKW121SPPQNYKKRV131AALEAKQKPS141TSQSQGLTRQ
151-200151DQMIAERLAR161LRQENKPKLV171PSQAEIEARL181AALKDERQGS191IPSTQEMEAR
201-250201LAALQGRVLP211SQTPQPAHHT221PDTRTQAQQT231QDLLTQLAAE241VAIDESWKGG
251-300251GPAASLQNDL261NQGGPGSTNS271KRQANWSLEE281EKSRLLAEAA291LELREENTRQ
301-350301ERILALAKRL311AMLRGQDPER321VTLQDYRLPD331SDDDEDEETA341IQRVLQQLTE
351-400351EASLDEASGF361NIPAEQASRP371WTQPRGAEPE381AQDVDPRPEA391EEEELPWCCI
401-448401CNEDATLRCA411GCDGDLFCAR421CFREGHDAFE431LKEHQTSAYS441PPRAGQEH
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
57 Prediction (Low) - -
60 Prediction (Low) - -
73 Prediction (Medium) - -
76 Prediction (Medium) - -
81 Prediction (Low) - -
84 Prediction (High) - -
102 Prediction (Low) - -
399 Prediction (Low) - -
412 Prediction (Low) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
125 C → Sfs*8 0.002294 DEL Frame Shift Del OV
136 S → C 0.002294 SNP Missense Mutation OV
143 W → C 0.002545 SNP Missense Mutation GBM
435 C → C 0.003774 SNP Silent UCEC
460 S → C 0.002427 SNP Missense Mutation BLCA
466 R → C 0.001887 SNP Missense Mutation UCEC