Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| H3BRM1 | ZFYVE19 | Abscission/NoCut checkpoint regulator (Zinc finger … | Homo sapiens (Human) | 307 aa |
Protein Details: H3BRM1 (ZFYVE19)
Protein Information
| Accession | H3BRM1 |
|---|---|
| Protein Names | Abscission/NoCut checkpoint regulator (Zinc finger FYVE domain-containing protein 19) |
| Gene Symbol | ZFYVE19 |
| Organism | Homo sapiens (Human) |
| Length | 307 aa |
| Isoforms | No isoforms |
| Related PMIDs | 29575903 31251020 36430497 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501GGTVPVGVWG11GAGQGREGRS21WGEGPRGPGL31GRRDLSSADP41AVLGATMESR
51-10051CYGCAVKFTL61FKKEYGCKNC71GRAFCSGCLS81FSAAVPRTGN91TQQKVCKQCH
101-150101EVLTRGSSAN111ASKWSPPQNY121KKRVAALEAK131QKPSTSQSQG141LTRQDQMIAE
151-200151RLARLRQENK161PKLVPSQAEI171EARLAALKDE181RQGSIPSTQE191MEARLAALQG
201-250201RVLPSQTPQP211AHHTPDTRTQ221AQQTQDLLTQ231LAAEVAIDES241WKGGGPGLPL
251-300251QVTLQDYRLP261DSDDDEDEET271AIQRVLQQLT281EEASLDEASG291FNIPAEQASR
301-307301PWTQPRG
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 51 | ABSCISSION/NOCUT CHECKPOINT REGULATOR Zinc finger, FYVE/PHD-type Zinc finger, RING/FYVE/PHD-type | - | - |
GPS-Palm: 0.72
Deep-Palm: 0.90
|
|
| 54 | - | - | - |
GPS-Palm: 0.72
Deep-Palm: 0.81
|
|
| 67 | - | - | - |
GPS-Palm: 0.80
Deep-Palm: 0.09
|
|
| 70 | - | - | - |
GPS-Palm: 0.87
Deep-Palm: 0.17
|
|
| 75 | - | - | - |
GPS-Palm: 0.71
Deep-Palm: 0.23
|
|
| 78 | - | - | - |
GPS-Palm: 0.91
Deep-Palm: 0.20
|
|
| 96 | - | - | - |
GPS-Palm: 0.77
Deep-Palm: 0.45
|
|
| 99 | - | - | - |
Deep-Palm: 0.40
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.571
4
cerebral cortex
Specificity: 0.571
4/4 (100.0%)
2
HeLa cell
Specificity: 0.286
2/2 (100.0%)
1
LNCaP
Specificity: 0.143
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 125 | C → Sfs*8 | 0.002294 | DEL | Frame Shift Del | OV |
| 136 | S → C | 0.002294 | SNP | Missense Mutation | OV |
| 143 | W → C | 0.002545 | SNP | Missense Mutation | GBM |
| 435 | C → C | 0.003774 | SNP | Silent | UCEC |
| 460 | S → C | 0.002427 | SNP | Missense Mutation | BLCA |
| 466 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |