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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
H3BTQ3 SLC19A1 Reduced folate transporter (Solute carrier … Homo sapiens (Human) 545 aa

Protein Details: H3BTQ3 (SLC19A1)

Protein Information
Accession H3BTQ3
Protein Names Reduced folate transporter (Solute carrier family 19 member 1)
Gene Symbol SLC19A1
Organism Homo sapiens (Human)
Length 545 aa
Isoforms No isoforms
Related PMIDs 19801377 29575903 31251020 32944167
Database Sources CysModDB dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.364
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
4
LNCaP cells
Specificity: 0.364
4/46 (8.7%)
4
PC3 cells
Specificity: 0.364
4/4 (100.0%)
2
DU145 cells
Specificity: 0.182
2/2 (100.0%)
1
HeLa cells
Specificity: 0.091
1/1 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MVPSSPAVEK11QVPVEPGPDP21ELRSWRHLVC31YLCFYGFMAQ41IRPGESFITP
51-10051YLLGPDKNFT61REQVTNEITP71VLSYSYLAVL81VPVFLLTDYL91RYTPVLLLQG
101-150101LSFVSVWLLL111LLGHSVAHMQ121LMELFYSVTM131AARIAYSSYI141FSLVRPARYQ
151-200151RVAGYSRAAV161LLGVFTSSVL171GQLLVTVGRV181SFSTLNYISL191AFLTFSVVLA
201-250201LFLKRPKRSL211FFNRDDRGRC221ETSASELERM231NPGPGGKLGH241ALRVACGDSV
251-300251LARMLRELGD261SLRRPQLRLW271SLWWVFNSAG281YYLVVYYVHI291LWNEVDPTTN
301-350301SARVYNGAAD311AASTLLGAIT321SFAAGFVKIR331WARWSKLLIA341GVTATQAGLV
351-400351FLLAHTRHPS361SIWLCYAAFV371LFRGSYQFLV381PIATFQIASS391LSKELCALVF
401-450401GVNTFFATIV411KTIITFIVSD421VRGLGLPVRK431QALRMSRPRL441GLCLPGPFPP
451-500451QSAAPARAGM461AASSAEDPGS471ERGPWRRAGT481VAARGDPGGE491RGPWRREGTL
501-545501AARGDPGGER511GPWWREGTLA521VRGDPGGERG531PWRREGTLVV541KGARG
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
33 Prediction (Low) - -
220 Prediction (Low) - -
246 CYSMODDB SWISSPALM DBPTM Prediction (Medium) - -
396 Prediction (Low) - -
443 Prediction (Medium) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
83 V → Cfs*121 0.005435 DEL Frame Shift Del ESCA
133 R → C 0.001887 SNP Missense Mutation UCEC
138 S → C 0.003460 SNP Missense Mutation CESC
148 R → C 0.003774 SNP Missense Mutation UCEC
149 Y → C 0.002747 SNP Missense Mutation LIHC
205 R → C 0.001887 SNP Missense Mutation UCEC
229 R → C 0.001887 SNP Missense Mutation UCEC
280 G → C 0.001887 SNP Missense Mutation UCEC
287 Y → C 0.001969 SNP Missense Mutation HNSC
331 W → C 0.001887 SNP Missense Mutation UCEC
333 R → C 0.005435 SNP Missense Mutation ESCA
370 V → Cfs*70 0.002020 DEL Frame Shift Del PRAD
429 R → C 0.002545 SNP Missense Mutation GBM
429 R → C 0.002033 SNP Missense Mutation LUSC